一名癌症患者因种植体周围药物相关性骨坏死而诱发牙髓病:病例报告。

IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE
André Caroli Rocha, Maria Emília Mota, Ricardo Costa Lima, Nayara Fernanda Pereira, Fabio Abreu Alves, Maria Stella Moreira
{"title":"一名癌症患者因种植体周围药物相关性骨坏死而诱发牙髓病:病例报告。","authors":"André Caroli Rocha, Maria Emília Mota, Ricardo Costa Lima, Nayara Fernanda Pereira, Fabio Abreu Alves, Maria Stella Moreira","doi":"10.1111/aej.12893","DOIUrl":null,"url":null,"abstract":"<p><p>Medication-related osteonecrosis of the jaw (MRONJ) is a progressive condition that can cause significant bone loss and its diagnosis can be challenging. A 68-year-old man with a diagnosis of hepatocellular carcinoma, undergoing treatment with atezolizumab, bevacizumab and zoledronic acid, complained of spontaneous pain in the right lower second premolar. Oral examination revealed no dental changes and implants in the right jaw. A patient history and thorough clinical and radiographic examinations mimic endodontic disease. The implant crowns were removed, bleeding on probing, and peri-implant pockets were observed. The main hypothesis was MRONJ Stage 2, and the surgical treatment was performed. The pain ceased and signs of MRONJ were not observed within 3 months. MRONJ should be considered as a hypothesis in the case of odontalgia and a patient's history of antiresorptive and antiangiogenic therapies. Furthermore, monitoring patients with dental implants in the mandible through detailed clinical and imaging evaluation is required.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Peri-implant medication-related osteonecrosis of the jaw mimicking endodontic disease in a cancer patient: A case report.\",\"authors\":\"André Caroli Rocha, Maria Emília Mota, Ricardo Costa Lima, Nayara Fernanda Pereira, Fabio Abreu Alves, Maria Stella Moreira\",\"doi\":\"10.1111/aej.12893\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Medication-related osteonecrosis of the jaw (MRONJ) is a progressive condition that can cause significant bone loss and its diagnosis can be challenging. A 68-year-old man with a diagnosis of hepatocellular carcinoma, undergoing treatment with atezolizumab, bevacizumab and zoledronic acid, complained of spontaneous pain in the right lower second premolar. Oral examination revealed no dental changes and implants in the right jaw. A patient history and thorough clinical and radiographic examinations mimic endodontic disease. The implant crowns were removed, bleeding on probing, and peri-implant pockets were observed. The main hypothesis was MRONJ Stage 2, and the surgical treatment was performed. The pain ceased and signs of MRONJ were not observed within 3 months. MRONJ should be considered as a hypothesis in the case of odontalgia and a patient's history of antiresorptive and antiangiogenic therapies. Furthermore, monitoring patients with dental implants in the mandible through detailed clinical and imaging evaluation is required.</p>\",\"PeriodicalId\":55581,\"journal\":{\"name\":\"Australian Endodontic Journal\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-10-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Australian Endodontic Journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/aej.12893\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Australian Endodontic Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/aej.12893","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0

摘要

药物相关性颌骨坏死(MRONJ)是一种可导致大量骨质流失的进展性疾病,其诊断可能具有挑战性。一名68岁的男性被诊断为肝细胞癌,正在接受阿替佐珠单抗、贝伐单抗和唑来膦酸治疗,主诉右下第二前磨牙自发疼痛。口腔检查显示牙齿无变化,右下颌有种植体。根据病史以及全面的临床和放射检查,该患者患有牙髓病。种植体牙冠已被拔除,探诊时发现有出血现象,种植体周围有牙周袋。主要假设是 MRONJ 2 期,并进行了手术治疗。3 个月内疼痛消失,也未观察到 MRONJ 的迹象。在牙痛和患者有抗骨质吸收和抗血管生成治疗史的情况下,应将 MRONJ 视为一种假说。此外,还需要通过详细的临床和影像学评估对下颌骨种植牙患者进行监测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Peri-implant medication-related osteonecrosis of the jaw mimicking endodontic disease in a cancer patient: A case report.

Medication-related osteonecrosis of the jaw (MRONJ) is a progressive condition that can cause significant bone loss and its diagnosis can be challenging. A 68-year-old man with a diagnosis of hepatocellular carcinoma, undergoing treatment with atezolizumab, bevacizumab and zoledronic acid, complained of spontaneous pain in the right lower second premolar. Oral examination revealed no dental changes and implants in the right jaw. A patient history and thorough clinical and radiographic examinations mimic endodontic disease. The implant crowns were removed, bleeding on probing, and peri-implant pockets were observed. The main hypothesis was MRONJ Stage 2, and the surgical treatment was performed. The pain ceased and signs of MRONJ were not observed within 3 months. MRONJ should be considered as a hypothesis in the case of odontalgia and a patient's history of antiresorptive and antiangiogenic therapies. Furthermore, monitoring patients with dental implants in the mandible through detailed clinical and imaging evaluation is required.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Australian Endodontic Journal
Australian Endodontic Journal DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
3.50
自引率
6.20%
发文量
99
审稿时长
>12 weeks
期刊介绍: The Australian Endodontic Journal provides a forum for communication in the different fields that encompass endodontics for all specialists and dentists with an interest in the morphology, physiology, and pathology of the human tooth, in particular the dental pulp, root and peri-radicular tissues. The Journal features regular clinical updates, research reports and case reports from authors worldwide, and also publishes meeting abstracts, society news and historical endodontic glimpses. The Australian Endodontic Journal is a publication for dentists in general and specialist practice devoted solely to endodontics. It aims to promote communication in the different fields that encompass endodontics for those dentists who have a special interest in endodontics.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信