泰国儿童食物过敏的早期生活风险因素和临床特征。

IF 1.3 Q3 PEDIATRICS
International Journal of Pediatrics Pub Date : 2024-10-14 eCollection Date: 2024-01-01 DOI:10.1155/2024/6767537
Samkhwan Thongsukkaeo, Yiwa Suksawat
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引用次数: 0

摘要

背景:全世界 1%-10%的五岁以下儿童患有食物过敏症,其中遗传和早期生活因素是主要原因。已报道的因素包括过敏性疾病家族史、个人特应性皮炎、剖腹产、孕期和哺乳期的饮食限制以及引入固体食物的时间。本研究旨在确定与食物过敏相关的各种因素,并评估每种食物过敏的临床特征。研究方法我们进行了一项病例对照研究,病例和对照组的参与者比例为 1:2。我们收集了两组参与者的数据,问卷内容包括居住地区、性别和出生史(出生详情、母亲孕期和哺乳期饮食、婴儿期喂养史、特应性疾病家族史和家庭吸烟史)。研究结果研究共纳入了 72 例食物过敏病例和 145 例对照组病例。足月分娩是发生食物过敏的一个保护因素(调整后的几率比 [aOR] 0.213,P 值 0.022)。与此相反,个人特应性皮炎(aOR 20.097,p 值 0.001)和过敏性疾病家族史则是危险因素(aOR 3.183,p 值 0.002)。食物过敏与剖腹产、低出生体重、哺乳期和孕期饮食限制、纯母乳喂养或过早添加辅食无关。最常见的三种食物过敏原分别是蛋白(40.2%)、小麦(34.7%)和牛奶(30.5%)。结论在这项研究中,与食物过敏相关的风险因素包括个人特应性皮炎病史和家族过敏性疾病,这些因素可作为泰国儿童发生食物过敏的预测因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Early-Life Risk Factors and Clinical Features of Food Allergy Among Thai Children.

Background: Food allergy affects 1%-10% of children under five worldwide, with genetic and early-life factors playing a primary role. Reported factors include a family history of allergic diseases, personal atopic dermatitis, cesarean section, dietary restrictions during pregnancy and lactation, and the timing of introducing solid foods. This study was aimed at identifying various factors associated with food allergy and evaluate each food allergy's clinical features. Methods: We conducted a case-control study with a participant ratio of 1:2 between cases and controls. Data were gathered from both groups of participants, and questionnaires included living area, sex, and natal history (birth details, maternal diet during pregnancy and breastfeeding, feeding history during infancy, family history of atopic diseases, and household smoking). Results: All 72 cases with food allergy and 145 controls were included in the study. Term birth comprised a protective factor for developing food allergy (adjusted odds ratio [aOR] 0.213, p value 0.022). In contrast, personal atopic dermatitis (aOR 20.097, p value 0.001) and a family history of allergic disease constituted risks (aOR 3.183, p value 0.002). Food allergy was unrelated to cesarean section, low birth weight, dietary restrictions during lactation and pregnancy, exclusive breastfeeding, or the early introduction of complementary foods. The three most common food allergens were egg white (40.2%), wheat (34.7%), and cow's milk (30.5%), respectively. Conclusions: In this study, risk factors associated with food allergy comprised a personal history of atopic dermatitis and a family allergic disease, which may be used as predictive factors for developing food allergy among Thai children.

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来源期刊
CiteScore
3.90
自引率
0.00%
发文量
0
审稿时长
4 weeks
期刊介绍: International Journal of Pediatrics is a peer-reviewed, open access journal that publishes original researcharticles, review articles, and clinical studies in all areas of pediatric research. The journal accepts submissions presented as an original article, short communication, case report, review article, systematic review, or letter to the editor.
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