巨噬细胞极化及其对骨质疏松症的影响

Q4 Biochemistry, Genetics and Molecular Biology

Results and Problems in Cell Differentiation Pub Date : 2024-01-01 DOI:10.1007/978-3-031-65944-7_11

Junwei Yan, Chenyu Huang, Dongdong Jiang, Yan Xu, Zhuoli Zhang, Liming Wang, Bin Liang

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引用次数: 0

摘要

由于骨密度降低和骨折风险增加，骨质疏松症仍然是一个国际公共卫生危机。研究强调了巨噬细胞极化在骨质疏松症中的重要作用，并指出促炎性 M1 巨噬细胞和抗炎性 M2 巨噬细胞之间的平衡影响着骨代谢。本综述探讨了 M1 和 M2 巨噬细胞如何导致骨质疏松症的发生，并评估了旨在控制巨噬细胞极化的现有治疗方法。它还描述了未来的研究领域，这些领域将有助于改善骨质疏松症的管理和治疗。

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Macrophage Polarization and Its Impact on Osteoporosis.

Owing to its reduced bone density and higher risk for fractures, osteoporosis remains an international public health crisis. Research highlights the essential role played by macrophage polarization in osteoporosis and indicates that the balance between pro-inflammatory M1 macrophages and anti-inflammatory M2 macrophages influences bone metabolism. This review examines how M1 and M2 macrophages contribute to the development of osteoporosis and evaluates existing therapeutic approaches aimed at controlling macrophage polarization. It also describes future study areas that will allow improved management and treatment of osteoporosis.

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来源期刊

Results and Problems in Cell Differentiation Biochemistry, Genetics and Molecular Biology-Developmental Biology

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： Results and Problems in Cell Differentiation is an up-to-date book series that presents and explores selected questions of cell and developmental biology. Each volume focuses on a single, well-defined topic. Reviews address basic questions and phenomena, but also provide concise information on the most recent advances. Together, the volumes provide a valuable overview of this exciting and dynamically expanding field.