超越药物:利用植物化合物的潜力进行抗炎治疗。

IF 1.2 Q4 PHARMACOLOGY & PHARMACY
Vishnu Mittal, Anjali Sharma
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引用次数: 0

摘要

血管组织对感染、受损细胞或刺激物等破坏性刺激的复杂生物反应称为炎症。症状包括关节发红、发炎、僵硬、不适以及关节功能丧失。非甾体抗炎药常用于治疗炎症。遗憾的是,这些药物有可能引发血栓,导致心脏病发作和中风。因此,目前的研究重点是利用天然成分开发强效消炎药。天然产品的化学成分多种多样,为开发新型药物提供了丰富的资源。各种炎症相关疾病的治疗在很大程度上依赖于从药用植物中提取的天然物质。本研究的目的是采用最先进的科学方法,收集有关用于炎症模型的植物潜在部分或从药用植物中提取的植物化学物质的信息。本研究采用最先进的科学方法来研究从药用植物中提取的植物化学物质的作用。研究收集了相关数据,重点考察了这些植物化学物质在炎症实验模型中的作用。本研究旨在收集有关药用植物中提取的潜在植物部分或有前景的植物化学物质的详尽数据,这些数据已在炎症模型领域使用先进的科学技术进行了评估。这一汇编将为了解它们作为抗炎剂的潜力提供宝贵的见解。与目前的治疗方法相比,这些研究结果有可能有助于开发新的、更好的抗炎药物,减少或消除不良反应。虽然这些研究中有许多都具有学术意义,但只有少数被纳入临床试验。目前已发现许多植物成分具有不同的药理作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Beyond Pharmaceuticals: Harnessing the Potential of Plant-based Compounds for Anti-inflammatory Therapy.

A complicated biological reaction of vascular tissues to damaging stimuli like infections, harmed cells, or irritants is called inflammation. Symptoms include redness, inflamed joints, stiffness, discomfort in the joints, and loss of joint function. NSAIDs are frequently used to treat inflammation. Sadly, these drugs raise the possibility of blood clots, which can result in heart attacks and strokes. Consequently, there is ongoing research focusing on developing potent anti-inflammatory drugs using natural ingredients. Natural products, due to their diverse chemical composition, offer a rich source for the development of novel medications. The treatment of various inflammation- related disorders heavily relies on a natural substance derived from medicinal plants. The objective of the present study is to assemble information on potential parts of the plants or phytochemicals derived from medicinal plants used on inflammatory models, employing state-ofthe- art scientific methodologies. In this study, state-of-the-art scientific methodologies are utilized to investigate the effects of phytochemicals derived from medicinal plants. Relevant data is collected, focusing on the examination of these phytochemicals in experimental models of inflammation. The study aims to collect thorough data on potential plant parts or promising phytochemicals derived from medicinal plants that have been evaluated using advanced scientific techniques in the realm of inflammation models. This compilation will offer valuable insights into their potential as anti-inflammatory agents. The findings have the potential to contribute to the development of new and improved anti-inflammatory medications with fewer or no adverse effects compared to current treatments. While many of these studies hold academic interest only a few are accepted into clinical trials. Numerous phytoconstituents have been identified for exhibiting diverse pharmacological actions.

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来源期刊
CiteScore
4.30
自引率
0.00%
发文量
33
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