对马来西亚红树林蝮蛇感染研究的关注。

IF 2.6 4区医学 Q2 PHARMACOLOGY & PHARMACY

Toxicon Pub Date : 2024-10-17 DOI:10.1016/j.toxicon.2024.108126

Ahmad Khaldun Ismail, David A. Warrell, Scott A. Weinstein

引用次数: 0

摘要

我们饶有兴趣地阅读了 Chan 及其同事撰写的题为 "马来西亚雪兰莪州中区集群医院红树林蝮蛇感染回顾性观察研究 "的论文（Toxicon 249, 108086），但对其中的一些内容表示担忧。首先，作者声称"所有被招募的患者均根据真实的蛇标本或照片证据被诊断为红树林蝮蛇咬伤，从而可以在临床上进行物种鉴定（图 1）"。然而，并没有具体记录由哪些人或专家服务机构正式提供了大概合格的标本鉴定和/或指定负责查毒的人的图像。这是一个重要的考虑因素，至少应在 "局限性 "中加以说明，如果有的话，也应在 "致谢 "中加以说明。该研究包含一些缺陷和误导性论断，特别是关于抗蛇毒血清的使用和一些临床观察结果的报告，而且对有关这一有趣物种的出版物、最近对其分类的修订以及毒蛇咬伤的临床影响的介绍不够充分。下面，我们将对其中最重要的内容发表评论，因为这些内容可能会影响对被毒蛇咬伤的病人的管理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Concerns regarding the study on mangrove pit viper envenomation in Malaysia

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来源期刊

Toxicon 医学-毒理学

CiteScore

4.80

自引率

10.70%

发文量

358

审稿时长

68 days

期刊介绍： Toxicon has an open access mirror Toxicon: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. An introductory offer Toxicon: X - full waiver of the Open Access fee. Toxicon''s "aims and scope" are to publish: -articles containing the results of original research on problems related to toxins derived from animals, plants and microorganisms -papers on novel findings related to the chemical, pharmacological, toxicological, and immunological properties of natural toxins -molecular biological studies of toxins and other genes from poisonous and venomous organisms that advance understanding of the role or function of toxins -clinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtained. -material on the use of toxins as tools in studying biological processes and material on subjects related to venom and antivenom problems. -articles on the translational application of toxins, for example as drugs and insecticides -epidemiological studies on envenoming or poisoning, so long as they highlight a previously unrecognised medical problem or provide insight into the prevention or medical treatment of envenoming or poisoning. Retrospective surveys of hospital records, especially those lacking species identification, will not be considered for publication. Properly designed prospective community-based surveys are strongly encouraged. -articles describing well-known activities of venoms, such as antibacterial, anticancer, and analgesic activities of arachnid venoms, without any attempt to define the mechanism of action or purify the active component, will not be considered for publication in Toxicon. -review articles on problems related to toxinology. To encourage the exchange of ideas, sections of the journal may be devoted to Short Communications, Letters to the Editor and activities of the affiliated societies.