一名服用塞马鲁肽的患者在接受上内镜检查时发生肺吸入。

IF 2.7 4区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Revista Espanola De Enfermedades Digestivas Pub Date : 2024-10-18 DOI:10.17235/reed.2024.10844/2024

Tao Dong, Lan Wang, Hanying Wang, Jun Xiao

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引用次数: 0

摘要

在过去的十年中，由于有大量证据表明胰高血糖素样肽-1 受体激动剂（GLP-1RA）对 2 型糖尿病和肥胖症有益，因此其使用量不断增加。然而，GLP-1RAs 的胃排空延迟效应引起了人们对上消化道内窥镜检查中胃食物潴留和肺炎吸入风险的担忧。有观察研究报告称，在服用 GLP-1RAs 的患者中，尤其是像塞马鲁肽这样的长效 GLP-1RAs 患者，胃内食物潴留的发生率有所增加。但由于缺乏高级别证据，GLP-1RAs 的使用与胃肠镜检查时吸入肺炎之间的关系仍不明确。我们报告了一例服用塞马鲁肽的患者在做胃肠造影术时吸入肺炎的病例。

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Pulmonary aspiration during upper endoscopy in a patient prescribed semaglutide.

The past decade has witnessed an increasing use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) owing to robust evidence of its benefits in type 2 diabetes and obesity. However, delay gastric emptying effect of GLP-1RAs has raised concerns for risk of gastric food retention and pneumonia aspiration during upper endoscopy. There have been observation studies reporting an increased incidence of gastric food retention among patients on GLP-1RAs, especially long-acting one like semaglutide. But the association between GLP-1RAs use and pneumonia aspiration during EGD remains unclear due to lack of high-level evidence. We report a case of pulmonary aspiration during EGD in a patient prescribed semaglutide.

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来源期刊

Revista Espanola De Enfermedades Digestivas 医学-胃肠肝病学

CiteScore

2.00

自引率

25.00%

发文量

400

审稿时长

6-12 weeks

期刊介绍： La Revista Española de Enfermedades Digestivas, Órgano Oficial de la Sociedad Española de Patología Digestiva (SEPD), Sociedad Española de Endoscopia Digestiva (SEED) y Asociación Española de Ecografía Digestiva (AEED), publica artículos originales, editoriales, revisiones, casos clínicos, cartas al director, imágenes en patología digestiva, y otros artículos especiales sobre todos los aspectos relativos a las enfermedades digestivas.