所罗门群岛折衷鹦鹉(Eclectus roratus solomonensis)非转移性睾丸圆形细胞瘤的新辅助化疗和手术切除获得成功。

IF 0.6 4区 农林科学 Q3 VETERINARY SCIENCES
Rachel Baden, Brian Speer, Michael Garner, Vanessa Hernández Urraca, Brenna Fitzgerald
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引用次数: 0

摘要

一只 24 岁的所罗门群岛雄性折衷鹦鹉(Eclectus roratus solomonensis)在一次年度体检中触及到了一个盲肠内肿块。最初的诊断检查包括全血细胞计数、血浆生化全套检查和腹腔超声波检查。计算机断层扫描高度提示睾丸肿块。患者接受了他莫昔芬和促性腺激素释放激素激动剂利优孕酮(leuprolide)和去氯羟孕酮(deslorelin)作为新辅助内分泌疗法。活检和组织学检查证实,睾丸肿块与圆形细胞瘤一致。作为新辅助化疗,患者接受了4次15毫克/千克的卡铂静脉注射,睾丸体积缩小了约95%。通过睾丸切除术切除了剩余的大块肿瘤,切缘整齐而狭窄。术后 7 个月,对比 CT 扫描未发现原肿块复发或转移的迹象。这是首例通过新辅助化疗和睾丸切除术成功治疗鹦鹉睾丸肿瘤的报告。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Successful Neoadjuvant Chemotherapy and Surgical Removal of a Nonmetastatic Testicular Round Cell Tumor in a Solomon Island Eclectus Parrot (Eclectus roratus solomonensis).

An intracoelomic mass was palpated on an annual exam of a 24-year-old male Solomon Island eclectus parrot (Eclectus roratus solomonensis). The initial diagnostic workup included a complete blood count, plasma biochemistry panel, and coelomic ultrasound. Computed tomography was highly suggestive of a testicular mass. Tamoxifen and the gonadotropin-releasing hormone agonists leuprolide and deslorelin were administered as neoadjunctive endocrine therapies. Biopsy and histologic examination confirmed a testicular mass consistent with a round cell tumor. Four doses of carboplatin 15 mg/kg IV were administered as neoadjunctive chemotherapy, and testicular size decreased by approximately 95%. The remaining gross tumor was removed via orchidectomy with clean but narrow margins. Seven months following surgery, a contrast CT scan did not show any evidence of recurrence of or metastasis from the original mass. This is the first report of successful treatment of a testicular tumor in a psittacine with neoadjuvant chemotherapy and orchidectomy.

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来源期刊
Journal of Avian Medicine and Surgery
Journal of Avian Medicine and Surgery 农林科学-兽医学
CiteScore
0.90
自引率
0.00%
发文量
52
审稿时长
>36 weeks
期刊介绍: The Journal of Avian Medicine and Surgery is an international journal of the medicine and surgery of both captive and wild birds. Published materials include scientific articles, case reports, editorials, abstracts, new research, and book reviews.
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