从蛋白质组学到诊断：结核病研究中的生物标志物发现。

IF 3.5 4区医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Current medicinal chemistry Pub Date : 2024-10-11 DOI:10.2174/0109298673346264241008110105

Jiarong Yang, Jianhua Zheng

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引用次数: 0

摘要

结核病（TB）是全球单一传染病致死的主要原因。早期准确的诊断有利于及时发现和及时治疗，从而降低疾病传播的风险，这对有效控制结核病至关重要。生物标志物为结核病诊断提供了宝贵的资源。蛋白质组技术已成为发现生物标志物的有力工具。在本视角中，我们将探讨蛋白质组技术如何促进结核病诊断生物标志物的发现。我们还探讨了在结核病诊断中增强生物标志物性能的挑战和前瞻性方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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From Proteomics to Diagnosis: Biomarker Discovery in Tuberculosis Research.

Tuberculosis (TB) is a leading cause of death from a single infectious disease worldwide. Early and accurate diagnosis is advantageous for timely detection and prompt treatment, thereby reducing the risk of disease transmission, which is essential for effective TB control. Biomarkers provide a valuable resource for TB diagnosis. Proteomic technologies have emerged as a powerful tool in biomarker discovery. In this perspective, we explore how proteomic technologies contribute to the discovery of TB diagnostic biomarkers. We also address the challenges and discuss prospective methods to augment the performance of biomarkers in diagnosing TB.

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来源期刊

Current medicinal chemistry 医学-生化与分子生物学

CiteScore

8.60

自引率

2.40%

发文量

468

审稿时长

3 months

期刊介绍： Aims & Scope Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.