转录组分析揭示了小鼠肾周脂肪中米色脂肪细胞标记基因的选择性高表达。

IF 1.4 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioscience, Biotechnology, and Biochemistry Pub Date : 2024-11-22 DOI:10.1093/bbb/zbae143

Yoshinori Misawa, Yu Takahashi, Takashi Sasaki, Ryuichiro Sato, Yoshio Yamauchi

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引用次数: 0

摘要

为了揭示健康小鼠内脏脂肪组织特性的差异，我们利用 RNA 测序技术进行了转录组分析。在内脏脂肪组织中，我们发现肾周脂肪组织只表达米色脂肪细胞标记，而表达白色脂肪细胞标记。这些结果表明肾周脂肪组织在生理和病理状态下都可能发挥特殊作用。

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Transcriptome analysis reveals selectively high expression of beige adipocyte marker genes in mouse perinephric fat.

To reveal the differences in the properties of visceral adipose tissue in healthy unstimulated mice, we performed transcriptome analysis using RNA sequencing. Among visceral adipose tissues, perinephric adipose tissue was found to exclusively express beige adipocyte markers while expressing white adipocyte markers. These results imply potential specific roles of perinephric adipose tissue in both physiological and pathological conditions.

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来源期刊

Bioscience, Biotechnology, and Biochemistry 生物-生化与分子生物学

CiteScore

3.50

自引率

0.00%

发文量

183

审稿时长

1 months

期刊介绍： Bioscience, Biotechnology, and Biochemistry publishes high-quality papers providing chemical and biological analyses of vital phenomena exhibited by animals, plants, and microorganisms, the chemical structures and functions of their products, and related matters. The Journal plays a major role in communicating to a global audience outstanding basic and applied research in all fields subsumed by the Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA).