产妇产前体外生命支持术后的新生儿预后。

IF 3.1 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Benjamin D Seadler, Ashanti Johnson, Britton B Donato, Weston G Andrews, Adhitya Ramamurthi, Adam Ubert, Lucian A Durham
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引用次数: 0

摘要

产前呼吸衰竭或心源性休克病例经体外生命支持(ECLS)治疗成功后,母亲和胎儿的存活率都很高。相比之下,有关这些新生儿产后预后的文献却很少。我们报告了一项单中心回顾性研究,研究对象是 2015 年 2 月至 2023 年 4 月期间所有产前 ECLS 成人病例及新生儿随访情况。七名患者符合纳入标准,产妇年龄为(32.0±5.5)岁(中位数±四分位数间距[IQR]),其中六名患者(86%)主要是由于呼吸衰竭,在妊娠 27.0±3.0 周时开始实施 ECLS。所有产妇和胎儿均在孕龄(29.0±4.5 周)时顺利分娩。所有新生儿均存活至出院回家,其中最常见的合并症是早产(7 例,100%)和支气管肺发育不良(3 例,43%)。在 1.4±1.2 年的随访期间,4 名患者(57%)接受了正式的神经发育测试,其中 2 名患者(50%)出现了发育迟缓,均与言语/语言有关。这些结果表明,接受产前 ECLS 的儿童存活率高,且无明显发病,但可能需要对神经发育迟缓进行随访。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neonatal Outcomes Following Maternal Antepartum Extracorporeal Life Support.

Cases of antepartum respiratory failure or cardiogenic shock treated successfully with extracorporeal life support (ECLS) with high rates of survival for both mother and fetus are well documented. In contrast, there is a paucity of literature on the outcomes of these neonates after delivery. We report a single-center retrospective study of all adult cases of antepartum ECLS from February 2015 to April 2023 with neonatal follow-up. Seven patients met inclusion criteria with a maternal age of 32.0±5.5 years (median ± interquartile range [IQR]), primarily due to respiratory failure in six (86%) patients, with ECLS initiation at 27.0±3.0 weeks gestation. All mothers and fetuses survived to delivery at a gestational age of 29.0±4.5 weeks. All neonates survived to discharge home with the most common comorbidities being prematurity in seven (100%) patients and bronchopulmonary dysplasia in three (43%). In a follow-up period of 1.4±1.2 years; four (57%) patients underwent formal neurodevelopmental testing and two (50%) had identified delays, both related to speech/language. These results suggest that children exposed to antenatal ECLS demonstrate high rates of survival without significant morbidity, but that follow-up for neurodevelopmental delays may be warranted.

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来源期刊
ASAIO Journal
ASAIO Journal 医学-工程:生物医学
CiteScore
6.60
自引率
7.10%
发文量
651
审稿时长
4-8 weeks
期刊介绍: ASAIO Journal is in the forefront of artificial organ research and development. On the cutting edge of innovative technology, it features peer-reviewed articles of the highest quality that describe research, development, the most recent advances in the design of artificial organ devices and findings from initial testing. Bimonthly, the ASAIO Journal features state-of-the-art investigations, laboratory and clinical trials, and discussions and opinions from experts around the world. The official publication of the American Society for Artificial Internal Organs.
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