IF 2.2 4区 生物学 Q3 BIOPHYSICS
Grzegorz Górski, Krzysztof Kucab
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引用次数: 0

摘要

动脉粥样硬化是循环系统的重要疾病之一,因为动脉粥样硬化斑块会严重破坏血流。因此,正确理解这些过程并巧妙地模拟血流非常重要。在我们的工作中,我们考虑了流经腹主动脉和髂动脉的血流,假设右髂动脉因动脉粥样硬化病变而狭窄。使用层流、标准 k - ω 和标准 k - ϵ 模型模拟了血流。结果表明,尽管使用了相同的初始条件,但血流速度和血流壁剪应力的分布取决于血流模拟模型的选择。对于 k - ϵ 模型,我们在动脉粥样硬化斑块上获得了比其他两个模型更高的速度和壁剪应力值。层流模型和 k - ω 模型预测在动脉粥样硬化病变后方的区域会出现较大的反向血流。这种效应与负壁剪应力有关。这两个模型得出的结果非常相似。我们获得的结果和文献报道的结果表明,k - ω 模型最适合用于血流分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Time-dependent simulation of blood flow through an abdominal aorta with iliac arteries.

Atherosclerosis is one of the important diseases of the circulatory system because atherosclerotic plaques cause significant disruption of blood flow. Therefore, it is very important to properly understand these processes and skillfully simulate blood flow. In our work, we consider blood flow through an abdominal aorta with iliac arteries, assuming that the right iliac artery is narrowed by an atherosclerotic lesion. Blood flow is simulated using the laminar, standard k - ω and standard k - ϵ models. The obtained results show that despite the use of identical initial conditions, the distribution of velocity flow and wall shear stress depends on the choice of flow simulation model. For the k - ϵ model, we obtain higher values of speed and wall shear stress on atherosclerotic plaque than in the other two models. The laminar and k - ω models predict larger areas where reverse blood flow occurs in the area behind the atherosclerotic lesion. This effect is associated with negative wall shear stress. These two models give very similar results. The results obtained by us, and those reported in the literature, indicate that k - ω model is the most suitable for blood flow analysis.

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来源期刊
European Biophysics Journal
European Biophysics Journal 生物-生物物理
CiteScore
4.30
自引率
0.00%
发文量
43
审稿时长
6-12 weeks
期刊介绍: The journal publishes papers in the field of biophysics, which is defined as the study of biological phenomena by using physical methods and concepts. Original papers, reviews and Biophysics letters are published. The primary goal of this journal is to advance the understanding of biological structure and function by application of the principles of physical science, and by presenting the work in a biophysical context. Papers employing a distinctively biophysical approach at all levels of biological organisation will be considered, as will both experimental and theoretical studies. The criteria for acceptance are scientific content, originality and relevance to biological systems of current interest and importance. Principal areas of interest include: - Structure and dynamics of biological macromolecules - Membrane biophysics and ion channels - Cell biophysics and organisation - Macromolecular assemblies - Biophysical methods and instrumentation - Advanced microscopics - System dynamics.
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