Mengmeng Zhang, Wei Zhou, Qingqing Wang, Ning Wang, Xin Wang, Youping Liu, Xin Di
{"title":"用于环境水中喹喔啉-1,4-二氧杂环类选择性富集的水兼容磁性分子印迹纳米复合材料。","authors":"Mengmeng Zhang, Wei Zhou, Qingqing Wang, Ning Wang, Xin Wang, Youping Liu, Xin Di","doi":"10.1039/d4ay01250j","DOIUrl":null,"url":null,"abstract":"<p><p>In this work, a novel water compatible core-shell magnetic molecularly imprinted nanocomposite (Fe<sub>3</sub>O<sub>4</sub>-COOH@MIPs) was synthesized in an acetonitrile-water reaction system by adopting carboxyl group-functionalized Fe<sub>3</sub>O<sub>4</sub> nanoparticles as the magnetic core, olaquindox as the template molecule and acrylamide as the functional monomer. The resulting Fe<sub>3</sub>O<sub>4</sub>-COOH@MIPs was characterized and applied as an adsorbent for magnetic solid-phase extraction (MSPE) of three quinoline-1,4-dioxides (QdNOs). The Fe<sub>3</sub>O<sub>4</sub>-COOH@MIPs possessed strong magnetic responsiveness, fast adsorption equilibrium rate (equilibrium within 5 min) and excellent selectivity. By coupling Fe<sub>3</sub>O<sub>4</sub>-COOH@MIPs based MSPE with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS), good linearity (<i>R</i><sup>2</sup> ≥ 0.9985) and low limits of detection (0.83-5.0 ng L<sup>-1</sup>) for QdNOs were obtained. Finally, the proposed method was applied to determine trace QdNOs in environmental water samples, and the recoveries were in the range of 68.08-99.88% with RSD less than 12.5%.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":null,"pages":null},"PeriodicalIF":2.7000,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A water compatible magnetic molecularly imprinted nanocomposite for the class-selective enrichment of quinoxaline-1,4-dioxides in environmental water.\",\"authors\":\"Mengmeng Zhang, Wei Zhou, Qingqing Wang, Ning Wang, Xin Wang, Youping Liu, Xin Di\",\"doi\":\"10.1039/d4ay01250j\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In this work, a novel water compatible core-shell magnetic molecularly imprinted nanocomposite (Fe<sub>3</sub>O<sub>4</sub>-COOH@MIPs) was synthesized in an acetonitrile-water reaction system by adopting carboxyl group-functionalized Fe<sub>3</sub>O<sub>4</sub> nanoparticles as the magnetic core, olaquindox as the template molecule and acrylamide as the functional monomer. The resulting Fe<sub>3</sub>O<sub>4</sub>-COOH@MIPs was characterized and applied as an adsorbent for magnetic solid-phase extraction (MSPE) of three quinoline-1,4-dioxides (QdNOs). The Fe<sub>3</sub>O<sub>4</sub>-COOH@MIPs possessed strong magnetic responsiveness, fast adsorption equilibrium rate (equilibrium within 5 min) and excellent selectivity. By coupling Fe<sub>3</sub>O<sub>4</sub>-COOH@MIPs based MSPE with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS), good linearity (<i>R</i><sup>2</sup> ≥ 0.9985) and low limits of detection (0.83-5.0 ng L<sup>-1</sup>) for QdNOs were obtained. Finally, the proposed method was applied to determine trace QdNOs in environmental water samples, and the recoveries were in the range of 68.08-99.88% with RSD less than 12.5%.</p>\",\"PeriodicalId\":64,\"journal\":{\"name\":\"Analytical Methods\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2024-10-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Analytical Methods\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1039/d4ay01250j\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical Methods","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4ay01250j","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
A water compatible magnetic molecularly imprinted nanocomposite for the class-selective enrichment of quinoxaline-1,4-dioxides in environmental water.
In this work, a novel water compatible core-shell magnetic molecularly imprinted nanocomposite (Fe3O4-COOH@MIPs) was synthesized in an acetonitrile-water reaction system by adopting carboxyl group-functionalized Fe3O4 nanoparticles as the magnetic core, olaquindox as the template molecule and acrylamide as the functional monomer. The resulting Fe3O4-COOH@MIPs was characterized and applied as an adsorbent for magnetic solid-phase extraction (MSPE) of three quinoline-1,4-dioxides (QdNOs). The Fe3O4-COOH@MIPs possessed strong magnetic responsiveness, fast adsorption equilibrium rate (equilibrium within 5 min) and excellent selectivity. By coupling Fe3O4-COOH@MIPs based MSPE with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS), good linearity (R2 ≥ 0.9985) and low limits of detection (0.83-5.0 ng L-1) for QdNOs were obtained. Finally, the proposed method was applied to determine trace QdNOs in environmental water samples, and the recoveries were in the range of 68.08-99.88% with RSD less than 12.5%.