锰催化羧酸、重氮化合物和叔胺的三组分偶联反应以合成 β-氨基酯

IF 3.7 2区化学 Q2 CHEMISTRY, APPLIED

Applied Organometallic Chemistry Pub Date : 2024-08-15 DOI:10.1002/aoc.7678

Rongxiang Chen, Xingshuo Li, Lanying Chen, Kai-Kai Wang, Changqing Miao

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引用次数: 0

摘要

在锰的催化下，羧酸、重氮化合物和叔胺发生了一种简单而高效的三组分偶联反应。该反应在温和的条件下顺利进行，以 O2 作为末端氧化剂，可以中等至良好的收率得到各种 β-氨基酯。在这一过程中，锰基碳自由基、单电子转移和亲核攻击融合成了一个反应体系。

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Mn-Catalyzed Three-Component Coupling Reactions of Carboxylic Acids, Diazo Compounds, and Tertiary Amines for the Synthesis of β-Amino Esters

A simple and efficient three-component coupling reaction of carboxylic acids, diazo compounds, and tertiary amines catalyzed by manganese has been described. This reaction proceeds smoothly under mild conditions to afford various β-amino esters in moderate to good yields by using O₂ as the terminal oxidant. In this process, Mn-based carbene radical, single-electron transfer, and nucleophilic attack were fused into a reaction system.

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来源期刊

Applied Organometallic Chemistry 化学-无机化学与核化学

CiteScore

7.80

自引率

10.30%

发文量

408

审稿时长

2.2 months

期刊介绍： All new compounds should be satisfactorily identified and proof of their structure given according to generally accepted standards. Structural reports, such as papers exclusively dealing with synthesis and characterization, analytical techniques, or X-ray diffraction studies of metal-organic or organometallic compounds will not be considered. The editors reserve the right to refuse without peer review any manuscript that does not comply with the aims and scope of the journal. Applied Organometallic Chemistry publishes Full Papers, Reviews, Mini Reviews and Communications of scientific research in all areas of organometallic and metal-organic chemistry involving main group metals, transition metals, lanthanides and actinides. All contributions should contain an explicit application of novel compounds, for instance in materials science, nano science, catalysis, chemical vapour deposition, metal-mediated organic synthesis, polymers, bio-organometallics, metallo-therapy, metallo-diagnostics and medicine. Reviews of books covering aspects of the fields of focus are also published.