使用四甲基联苯胺共轭金纳米花对甲醛进行微流纸基比色化学传感：挥发性有机化合物高效化学传感的点对点方法

IF 4.1 3区化学 Q2 CHEMISTRY, PHYSICAL

Journal of Photochemistry and Photobiology A-chemistry Pub Date : 2024-10-01 DOI:10.1016/j.jphotochem.2024.116055

Fatemeh Farshchi , Sanna Ghaffarzadeh , Mohammad Hasanzadeh , Nasrin Shadjou

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引用次数: 0

摘要

甲醛是一种常见的环境醛类物质，也是一种公认的致癌物质，它的存在对人类健康构成重大威胁。监测环境样本和人体生物液体中的甲醛含量对于污染控制和健康科学的发展都至关重要。本研究介绍了一种有效的比色法，利用紫外可见光谱来识别真实样本中的甲醛。研究人员采用了各种尺寸和结构的金纳米粒子（AuNPs）来开发一种光化学化学传感装置。该方法检测甲醛的灵敏度很高，尤其是在 pH 值为 6.15 时使用金纳米花（AuNFs），定量限低至 0.1 µM，线性范围为 0.6 µM 至 1 M。此外，该方法还结合了一种基于纸张的微流控比色光学装置，用于现场和按需筛查甲醛。这项研究展示了 AuNPs 在精确灵敏检测人体生物液体中甲醛方面的应用，为针对甲醛和其他挥发性有机化合物 (VOC) 的先进分析方法提供了潜力。微流体纸基比色装置（µPCDs）的实用性、经济性和便携性使其成为床旁挥发性有机化合物检测的理想选择。这是 µPCDs 首次用于有毒物质的选择性光化学传感，其一步法过程不依赖于新型吸附剂、膜或外部刺激，因此很容易扩展。µPCD 广泛应用于选择性监测复杂生物基质中的甲醛的潜力显而易见。该方法在准确性、灵敏度、再现性和选择性方面都表现出了强大的性能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Microfluidic paper-based colorimetric chemo-sensing of formaldehyde using tetramethylbenzidine-conjugated gold nanoflowers: A point-on-demand approach for efficient chemosensing of volatile organic compounds

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The presence of formaldehyde, a common environmental aldehyde and a recognized carcinogen, poses a significant health risk to humans. Monitoring its levels in environmental samples and human biofluids is crucial for both pollution control and advancements in health science. This study introduces an effective colorimetric method utilizing UV–Vis spectroscopy to identify formaldehyde in real samples. Various types of gold nanoparticles (AuNPs) with diverse sizes and structures were employed to develop a photochemical chemosensing device. The method exhibited high sensitivity in detecting formaldehyde, particularly through the use of gold nanoflowers (AuNFs) at a pH of 6.15, with a low quantification limit of 0.1 µM and a linear range of 0.6 µM to 1 M. Furthermore, the method was successfully utilized to assess formaldehyde in human biofluids. Additionally, a paper-based microfluidic colorimetric opto-device was incorporated for on-site and on-demand formaldehyde screening. This study showcases the application of AuNPs for the precise and sensitive detection of formaldehyde in human biofluids, offering potential for advanced analytical methods targeted at formaldehyde and other volatile organic compounds (VOCs). The practicality, affordability, and portability of the microfluidic paper-based colorimetric device (µPCDs) make it a promising choice for point-of-care VOC testing. This represents the first demonstration of µPCDs for the selective photochemical sensing of toxic substances, and its one-step process that does not rely on novel sorbents, membranes, or external stimuli, making it easily scalable. The potential for µPCDs to be broadly applicable to the selective monitoring of formaldehyde from complex bio-matrices is evident. This method demonstrated robust performance in terms of accuracy, sensitivity, reproducibility, and selectivity.

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来源期刊

Journal of Photochemistry and Photobiology A-chemistry 化学-物理化学

CiteScore

7.90

自引率

7.00%

发文量

580

审稿时长

48 days

期刊介绍： JPPA publishes the results of fundamental studies on all aspects of chemical phenomena induced by interactions between light and molecules/matter of all kinds. All systems capable of being described at the molecular or integrated multimolecular level are appropriate for the journal. This includes all molecular chemical species as well as biomolecular, supramolecular, polymer and other macromolecular systems, as well as solid state photochemistry. In addition, the journal publishes studies of semiconductor and other photoactive organic and inorganic materials, photocatalysis (organic, inorganic, supramolecular and superconductor). The scope includes condensed and gas phase photochemistry, as well as synchrotron radiation chemistry. A broad range of processes and techniques in photochemistry are covered such as light induced energy, electron and proton transfer; nonlinear photochemical behavior; mechanistic investigation of photochemical reactions and identification of the products of photochemical reactions; quantum yield determinations and measurements of rate constants for primary and secondary photochemical processes; steady-state and time-resolved emission, ultrafast spectroscopic methods, single molecule spectroscopy, time resolved X-ray diffraction, luminescence microscopy, and scattering spectroscopy applied to photochemistry. Papers in emerging and applied areas such as luminescent sensors, electroluminescence, solar energy conversion, atmospheric photochemistry, environmental remediation, and related photocatalytic chemistry are also welcome.