Kevin Renz Ambrocio, Rohit Aggarwal, David Lacomis, Xingyu Zhang, Kendrea L Focht Garand
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We compared MBSImP Overall Impression (OI), Oral Total (OT), Pharyngeal Total (PT), and FOIS scores between groups. Specific to the IBM cohort, we analyzed repeated OT and PT scores and calculated whether age, sex, and OT and PT scores predicted FOIS scores.</p><p><strong>Results: </strong>The IBM cohort demonstrated poorer OI scores across six swallowing components than healthy controls (each <i>p</i> < .05). Unlike OT scores (<i>p</i> = .84), PT (<i>p</i> = .033) and FOIS (<i>p</i> < .001) scores were worse in the IBM cohort. Repeated OI scores revealed changes in three swallowing components (each <i>p</i> < .05), but repeated OT (<i>p</i> = .16) and PT (<i>p</i> = .30) scores did not significantly change. Age, sex, and OT and PT scores did not influence FOIS scores (each <i>p</i> > .05).</p><p><strong>Conclusions: </strong>Pharyngeal impairments were most prominent in the IBM cohort, and their oral intake status was adversely affected. Our preliminary data showcase the application of robust assessment methods to investigate swallowing function in IBM, enhancing standardization and comparability across studies.</p><p><strong>Supplemental material: </strong>https://doi.org/10.23641/asha.27165450.</p>","PeriodicalId":49240,"journal":{"name":"American Journal of Speech-Language Pathology","volume":" ","pages":"2793-2804"},"PeriodicalIF":2.3000,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11546978/pdf/","citationCount":"0","resultStr":"{\"title\":\"Features of Swallowing Function in Sporadic Inclusion Body Myositis: Preliminary Evidence Using Well-Tested Assessment Frameworks.\",\"authors\":\"Kevin Renz Ambrocio, Rohit Aggarwal, David Lacomis, Xingyu Zhang, Kendrea L Focht Garand\",\"doi\":\"10.1044/2024_AJSLP-24-00061\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Evidence surrounding swallowing impairment in sporadic inclusion body myositis (IBM) is based on nonstandardized and nonvalidated assessment methods. We investigated (a) IBM's impact on swallowing function and oral intake status using well-tested assessment frameworks; (b) changes in swallowing over time; and (c) age, sex, and swallowing impairment severity's influence on oral intake status.</p><p><strong>Method: </strong>We conducted a secondary analysis of Modified Barium Swallow Impairment Profile (MBSImP) and Functional Oral Intake Scale (FOIS) data from 13 patients with IBM (seven females; <i>M</i><sub>age</sub> = 60.2 [±13.6] years) and 13 age- and sex-matched healthy controls. We compared MBSImP Overall Impression (OI), Oral Total (OT), Pharyngeal Total (PT), and FOIS scores between groups. Specific to the IBM cohort, we analyzed repeated OT and PT scores and calculated whether age, sex, and OT and PT scores predicted FOIS scores.</p><p><strong>Results: </strong>The IBM cohort demonstrated poorer OI scores across six swallowing components than healthy controls (each <i>p</i> < .05). Unlike OT scores (<i>p</i> = .84), PT (<i>p</i> = .033) and FOIS (<i>p</i> < .001) scores were worse in the IBM cohort. Repeated OI scores revealed changes in three swallowing components (each <i>p</i> < .05), but repeated OT (<i>p</i> = .16) and PT (<i>p</i> = .30) scores did not significantly change. Age, sex, and OT and PT scores did not influence FOIS scores (each <i>p</i> > .05).</p><p><strong>Conclusions: </strong>Pharyngeal impairments were most prominent in the IBM cohort, and their oral intake status was adversely affected. 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引用次数: 0
摘要
目的：有关散发性包涵体肌炎（IBM）吞咽功能障碍的证据均基于非标准化和未经验证的评估方法。我们研究了（a）IBM 使用经过严格测试的评估框架对吞咽功能和口腔摄入状况的影响；（b）吞咽功能随时间的变化；以及（c）年龄、性别和吞咽功能障碍严重程度对口腔摄入状况的影响：我们对 13 名 IBM 患者（7 名女性；年龄 = 60.2 [±13.6] 岁）和 13 名年龄与性别匹配的健康对照者的改良钡吞咽功能障碍量表（MBSImP）和功能性口腔摄入量表（FOIS）数据进行了二次分析。我们比较了不同组间的 MBSImP 总体印象 (OI)、口腔总分 (OT)、咽部总分 (PT) 和 FOIS 分数。针对 IBM 组群，我们分析了重复的 OT 和 PT 分数，并计算了年龄、性别、OT 和 PT 分数是否能预测 FOIS 分数：结果：与健康对照组相比，IBM 组群在六项吞咽功能方面的 OI 评分均较低（每项 p < .05）。与 OT 分数（p = .84）不同，PT（p = .033）和 FOIS（p < .001）分数在 IBM 群体中更差。重复的 OI 分数显示了三个吞咽成分的变化（每个 p < .05），但重复的 OT (p = .16) 和 PT (p = .30) 分数没有显著变化。年龄、性别、OT和PT评分对FOIS评分没有影响（各P>.05）：结论：咽部功能障碍在 IBM 群体中最为突出，他们的口腔摄入状况也受到了不利影响。我们的初步数据展示了应用可靠的评估方法调查 IBM 吞咽功能的可行性，从而提高了各项研究的标准化和可比性。补充材料：https://doi.org/10.23641/asha.27165450。
Features of Swallowing Function in Sporadic Inclusion Body Myositis: Preliminary Evidence Using Well-Tested Assessment Frameworks.
Purpose: Evidence surrounding swallowing impairment in sporadic inclusion body myositis (IBM) is based on nonstandardized and nonvalidated assessment methods. We investigated (a) IBM's impact on swallowing function and oral intake status using well-tested assessment frameworks; (b) changes in swallowing over time; and (c) age, sex, and swallowing impairment severity's influence on oral intake status.
Method: We conducted a secondary analysis of Modified Barium Swallow Impairment Profile (MBSImP) and Functional Oral Intake Scale (FOIS) data from 13 patients with IBM (seven females; Mage = 60.2 [±13.6] years) and 13 age- and sex-matched healthy controls. We compared MBSImP Overall Impression (OI), Oral Total (OT), Pharyngeal Total (PT), and FOIS scores between groups. Specific to the IBM cohort, we analyzed repeated OT and PT scores and calculated whether age, sex, and OT and PT scores predicted FOIS scores.
Results: The IBM cohort demonstrated poorer OI scores across six swallowing components than healthy controls (each p < .05). Unlike OT scores (p = .84), PT (p = .033) and FOIS (p < .001) scores were worse in the IBM cohort. Repeated OI scores revealed changes in three swallowing components (each p < .05), but repeated OT (p = .16) and PT (p = .30) scores did not significantly change. Age, sex, and OT and PT scores did not influence FOIS scores (each p > .05).
Conclusions: Pharyngeal impairments were most prominent in the IBM cohort, and their oral intake status was adversely affected. Our preliminary data showcase the application of robust assessment methods to investigate swallowing function in IBM, enhancing standardization and comparability across studies.
期刊介绍：
Mission: AJSLP publishes peer-reviewed research and other scholarly articles on all aspects of clinical practice in speech-language pathology. The journal is an international outlet for clinical research pertaining to screening, detection, diagnosis, management, and outcomes of communication and swallowing disorders across the lifespan as well as the etiologies and characteristics of these disorders. Because of its clinical orientation, the journal disseminates research findings applicable to diverse aspects of clinical practice in speech-language pathology. AJSLP seeks to advance evidence-based practice by disseminating the results of new studies as well as providing a forum for critical reviews and meta-analyses of previously published work.
Scope: The broad field of speech-language pathology, including aphasia; apraxia of speech and childhood apraxia of speech; aural rehabilitation; augmentative and alternative communication; cognitive impairment; craniofacial disorders; dysarthria; fluency disorders; language disorders in children; speech sound disorders; swallowing, dysphagia, and feeding disorders; and voice disorders.
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