Ajay Vikram Singh, Vaisali Chandrasekar, Varsha M Prabhu, Jolly Bhadra, Peter Laux, Preeti Bhardwaj, Abdulla A Al-Ansari, Omar M Aboumarzouk, Andreas Luch, Sarada Prasad Dakua
{"title":"用于再生医学的可持续生物启发材料:平衡毒理学、环境影响和伦理考虑。","authors":"Ajay Vikram Singh, Vaisali Chandrasekar, Varsha M Prabhu, Jolly Bhadra, Peter Laux, Preeti Bhardwaj, Abdulla A Al-Ansari, Omar M Aboumarzouk, Andreas Luch, Sarada Prasad Dakua","doi":"10.1088/1748-605X/ad85bb","DOIUrl":null,"url":null,"abstract":"<p><p>The pursuit of sustainable bioinspired materials for regenerative medicine demands a nuanced balance between scientific advancement, ethical considerations, and environmental consciousness. This abstract encapsulates a comprehensive perspective paper exploring the intricate dynamics of toxicology, environmental impact, and ethical concerns within the realm of bioinspired materials. As the landscape of regenerative medicine evolves, ensuring the biocompatibility and safety of these materials emerges as a pivotal challenge. Our paper delves into the multidimensional aspects of toxicity assessment, encompassing cytotoxicity, genotoxicity, and immunotoxicity analyses. Additionally, we shed light on the complexities of evaluating the environmental impact of bioinspired materials, discussing methodologies such as life cycle assessment, biodegradability testing, and sustainable design approaches. Amid these scientific endeavors, we emphasize the paramount importance of ethical considerations in bioinspired material development, navigating the intricate web of international regulations and ethical frameworks guiding medical materials. Furthermore, our abstract underscores the envisioned future directions and challenges in toxicology techniques, computational modeling, and holistic evaluation, aiming for a comprehensive understanding of the synergistic interplay between sustainable bioinspired materials, toxicity assessment, environmental stewardship, and ethical deliberation.</p>","PeriodicalId":72389,"journal":{"name":"Biomedical materials (Bristol, England)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sustainable bioinspired materials for regenerative medicine: balancing toxicology, environmental impact, and ethical considerations.\",\"authors\":\"Ajay Vikram Singh, Vaisali Chandrasekar, Varsha M Prabhu, Jolly Bhadra, Peter Laux, Preeti Bhardwaj, Abdulla A Al-Ansari, Omar M Aboumarzouk, Andreas Luch, Sarada Prasad Dakua\",\"doi\":\"10.1088/1748-605X/ad85bb\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The pursuit of sustainable bioinspired materials for regenerative medicine demands a nuanced balance between scientific advancement, ethical considerations, and environmental consciousness. 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Sustainable bioinspired materials for regenerative medicine: balancing toxicology, environmental impact, and ethical considerations.
The pursuit of sustainable bioinspired materials for regenerative medicine demands a nuanced balance between scientific advancement, ethical considerations, and environmental consciousness. This abstract encapsulates a comprehensive perspective paper exploring the intricate dynamics of toxicology, environmental impact, and ethical concerns within the realm of bioinspired materials. As the landscape of regenerative medicine evolves, ensuring the biocompatibility and safety of these materials emerges as a pivotal challenge. Our paper delves into the multidimensional aspects of toxicity assessment, encompassing cytotoxicity, genotoxicity, and immunotoxicity analyses. Additionally, we shed light on the complexities of evaluating the environmental impact of bioinspired materials, discussing methodologies such as life cycle assessment, biodegradability testing, and sustainable design approaches. Amid these scientific endeavors, we emphasize the paramount importance of ethical considerations in bioinspired material development, navigating the intricate web of international regulations and ethical frameworks guiding medical materials. Furthermore, our abstract underscores the envisioned future directions and challenges in toxicology techniques, computational modeling, and holistic evaluation, aiming for a comprehensive understanding of the synergistic interplay between sustainable bioinspired materials, toxicity assessment, environmental stewardship, and ethical deliberation.