CAR-T 疗法的快速制造:战略与影响。

IF 14.3 1区 工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Sixun Chen, Dan Liu
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引用次数: 0

摘要

自体嵌合抗原受体 T 细胞(CAR-T)疗法的可及性受到复杂工艺和生产能力限制的挑战。能够缩短制造时间的快速制造技术可以改变 CAR-T 领域。在此,我们概述了快速 CAR-T 生产的方法,并强调了其对该领域各利益相关者的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rapid manufacturing of CAR-T therapy: strategies and impact.

The accessibility of autologous chimeric antigen receptor T cell (CAR-T) therapies is challenged by the complex processes and capacity constraints of manufacturing. Rapid manufacturing capable of shortening manufacturing timelines could transform the CAR-T field. Here, we outline approaches to rapid CAR-T manufacturing, highlighting its impact on various stakeholders in the landscape.

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来源期刊
Trends in biotechnology
Trends in biotechnology 工程技术-生物工程与应用微生物
CiteScore
28.60
自引率
1.20%
发文量
198
审稿时长
1 months
期刊介绍: Trends in Biotechnology publishes reviews and perspectives on the applied biological sciences, focusing on useful science applied to, derived from, or inspired by living systems. The major themes that TIBTECH is interested in include: Bioprocessing (biochemical engineering, applied enzymology, industrial biotechnology, biofuels, metabolic engineering) Omics (genome editing, single-cell technologies, bioinformatics, synthetic biology) Materials and devices (bionanotechnology, biomaterials, diagnostics/imaging/detection, soft robotics, biosensors/bioelectronics) Therapeutics (biofabrication, stem cells, tissue engineering and regenerative medicine, antibodies and other protein drugs, drug delivery) Agroenvironment (environmental engineering, bioremediation, genetically modified crops, sustainable development).
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