减肥手术后倾倒和低血糖症状的发生率:基于问卷的横断面研究。

IF 2.2 Q3 ENDOCRINOLOGY & METABOLISM
Clinical Obesity Pub Date : 2024-10-11 DOI:10.1111/cob.12709
Anders Jans, Eva Rask, Johan Ottosson, Eva Szabo, Erik Stenberg
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引用次数: 0

摘要

倾倒和减肥后低血糖(PBH)是减肥手术后出现的副作用。本研究的目的是在瑞典人群中估计鲁式胃旁路术(RYGB)和袖状胃切除术(SG)术前、术后6个月、1年、2年和5年的倾倒和低血糖症状的发生率。这项横断面单中心研究于 2020 年至 2023 年在瑞典厄勒布鲁地区的 Lindesberg 医院进行。研究采用了瑞典版倾倒严重程度量表(DSS-Swe)问卷,其中包括8个倾倒症状项目和6个低血糖症状项目。共纳入了 742 份 DSS-Swe 问卷。手术时的平均年龄为 42.0 岁(标准差 [SD] = 11.9),平均体重指数为 41.8 kg/m2(标准差 = 5.9)。手术方法包括 RYGB(66.3%)和 SG(33.7%)。高度疑似倾倒的 RYGB 患者比例从术前的 4.9% 增加到 5 年随访时的 26.3%(调整后的几率比 [OR] = 7.35,95% 置信区间 [CI] = 3.08-17.52)。PBH 症状从术前的 1.4% 增加到随访 5 年的 19.3%(调整后 OR = 17.88,95% 置信区间 [CI] = 4.07-78.54)。SG患者的倾倒或PBH症状没有明显增加。在持续性 2 型糖尿病 (T2D) 患者中,RYGB 或 SG 术后均未出现高度疑似低血糖的病例。RYGB 术后常见倾倒和 PBH 症状,而 SG 术后未观察到明显增加。持续的 T2D 似乎是 PBH 症状的保护因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of dumping and hypoglycaemia symptoms after bariatric surgery: A questionnaire-based cross-sectional study.

Dumping and post-bariatric hypoglycaemia (PBH) are side effects that occur after bariatric surgery. The aim of this study was to estimate the prevalence of dumping and PBH symptoms before Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) at 6 months, 1 year, 2 years and 5 years after surgery in a Swedish population. A cross-sectional single-centre study was performed at Lindesberg Hospital, Region Örebro County, Sweden, between 2020 and 2023. The Swedish version of the Dumping Severity Scale (DSS-Swe) questionnaire, which includes eight items regarding dumping symptoms and six items regarding hypoglycaemia symptoms, was used. A total of 742 DSS-Swe questionnaires were included. The average age at surgery was 42.0 years (standard deviation [SD] = 11.9), and the average body mass index was 41.8 kg/m2 (SD = 5.9). The surgical methods consisted of RYGB (66.3%) and SG (33.7%). The proportion of RYGB patients with highly suspected dumping increased from 4.9% before surgery to 26.3% (adjusted odds ratio [OR] = 7.35, 95% confidence interval [CI] = 3.08-17.52) at the 5-year follow-up. PBH symptoms increased from 1.4% before surgery to 19.3% at the 5-year follow-up (adjusted OR = 17.88, 95% CI = 4.07-78.54). For SG patients, no significant increase in dumping or PBH symptoms was observed. In patients with persistent type 2 diabetes (T2D), there were no cases of highly suspected hypoglycaemia following RYGB or SG. Symptoms of dumping and PBH were common after RYGB, while no clear increase was observed after SG. Persistent T2D seems to be a protective factor against PBH symptoms.

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来源期刊
Clinical Obesity
Clinical Obesity ENDOCRINOLOGY & METABOLISM-
CiteScore
5.90
自引率
3.00%
发文量
59
期刊介绍: Clinical Obesity is an international peer-reviewed journal publishing high quality translational and clinical research papers and reviews focussing on obesity and its co-morbidities. Key areas of interest are: • Patient assessment, classification, diagnosis and prognosis • Drug treatments, clinical trials and supporting research • Bariatric surgery and follow-up issues • Surgical approaches to remove body fat • Pharmacological, dietary and behavioural approaches for weight loss • Clinical physiology • Clinically relevant epidemiology • Psychological aspects of obesity • Co-morbidities • Nursing and care of patients with obesity.
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