评估人工耳蜗植入者电极植入创伤引起的残余听力损失的进展及其意义--叙述性综述。

IF 0.6 Q4 SURGERY
Nidhin Das, Vidhu Sharma, Amit Goyal
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引用次数: 0

摘要

人工耳蜗植入手术彻底改变了重度听力损失的治疗方法,越来越多的人开始关注保护残余听力,尤其是低频听力。本综述总结了有关人工耳蜗植入技术、手术原理以及旨在减少植入后听力损失的新兴疗法的现有文献。在方法上,我们进行了全面的叙事性文献综述,包括各种研究设计和参与者的人口统计学特征。检索策略涉及主要的生物医学数据库,重点是英文文章。软手术 "等外科技术强调尽量减少耳蜗所受的机械压力,而药理药剂方面的进步则是探索使用皮质类固醇、神经营养素和生长因子来增强听力保护。电极设计和插入策略也在不断发展,包括考虑插入力和电极阵列设计,以尽量减少创伤和优化听力结果。残余听力损失的评估涉及耳电图和放射成像等复杂技术。残余听力对听觉言语结果的影响不尽相同,有研究表明,残余听力与语言发展,尤其是语言表达能力的发展呈正相关。电极设计、手术技术和给药方面的新策略有望改善人工耳蜗植入术的效果。然而,缺乏标准化指南和需要进一步临床试验等挑战依然存在。未来的发展方向包括探索纳米技术、基因疗法和干细胞来构建仿生耳,尽管伦理和技术障碍依然存在。这篇综述强调了目前为提高人工耳蜗植入功能所做的努力,以及继续开展研究以优化听力损失患者治疗效果的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Advances in Evaluation of Electrode Insertion Trauma Induced Residual Hearing loss in Cochlear Implant Recipients and its significance- A Narrative Review.

Cochlear implant surgery has revolutionized the management of profound hearing loss, with a growing focus on preserving residual hearing, particularly low-frequency hearing. This review synthesizes existing literature on cochlear implantation techniques, surgical principles, and emerging therapies aimed at reducing post-implantation hearing loss. Methodologically, a comprehensive narrative literature review was conducted, encompassing various study designs and participant demographics. The search strategy involved major biomedical databases, focusing on articles in English. Surgical techniques such as "soft surgery" emphasize minimizing mechanical stress on the cochlea, while advancements in pharmacological agents explore the use of corticosteroids, neurotrophins, and growth factors to enhance hearing preservation. Electrode design and insertion strategies are evolving to minimize trauma and optimize hearing outcomes, including consideration of insertion forces and electrode array designs. Evaluating residual hearing loss involves sophisticated techniques like electrocochleography and radiological imaging. The impact of residual hearing on auditory verbal outcomes is variable, with studies indicating positive correlations with language development, particularly in speech production. Emerging strategies in electrode design, surgical techniques, and drug delivery hold promise for improving outcomes in cochlear implantation. However, challenges such as the lack of standardized guidelines and the need for further clinical trials remain. Future directions include the exploration of nanotechnologies, gene therapies, and stem cells for constructing bionic ears, although ethical and technical hurdles persist. This review underscores the ongoing efforts to enhance cochlear implant functionality and the need for continued research to optimize outcomes for patients with hearing loss.

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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
226
审稿时长
6-12 weeks
期刊介绍: Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress. IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc. The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world. The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members. Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.
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