抗菌肽在家禽业中的应用。

IF 2.4 2区农林科学 Q3 MICROBIOLOGY

Veterinary microbiology Pub Date : 2024-09-27 DOI:10.1016/j.vetmic.2024.110267

Letícia Ferreira Lima , Kamila Botelho Sampaio de Oliveira , Karen Ofuji Osiro , Victor Albuquerque Cunha , Octávio Luiz Franco

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引用次数: 0

摘要

禽肉生产和出口对全球经济贡献巨大。然而，各种感染会影响家禽生产，进而影响经济。如今，抗生素被广泛用于治疗和预防感染。抗生素的过度使用是一个问题，因为它可能会导致抗菌素耐药性，而这种耐药性可能会直接或间接传染给人类，从而影响公众健康。此外，由于用于刺激动物生长的抗生素已被禁用，因此寻找新的分子来克服这些困难非常重要。作为一种替代品，抗菌肽（AMPs）具有免疫调节、抗菌和刺激生长的作用，因此这些分子有望成为抗生素的替代品。研究 AMPs 可为治疗影响家禽的最重要感染提供新思路。此外，这还有助于减少抗药性问题。本综述旨在探讨近期针对可能影响家禽业的病原体使用 AMPs 的研究。

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Application of antimicrobial peptides in the poultry industry

Poultry meat production and exportation contribute significantly to the global economy. However, various infections affect poultry production and consequently affect the economy. Nowadays, antibiotics are widely used in infection treatment and prevention. Antibiotic overuse is problematic because may cause antimicrobial resistance, which can be transferred to humans directly or indirectly, affecting public health. In addition, since antibiotics for animal growth stimulation are banned, it is important to search for new molecules to overcome these difficulties. As an alternative, antimicrobial peptides (AMPs) can show immunomodulatory, antimicrobial, and growth stimulation, which makes these molecules interesting as alternatives to antibiotic use. Studying AMPs can provide new ideas for treating the most important infections that affect poultry. Besides, this can assist in reducing the resistance problem. This review aims to examine recent studies about AMPs used against pathogens that can affect the poultry industry.

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来源期刊

Veterinary microbiology 农林科学-兽医学

CiteScore

5.90

自引率

6.10%

发文量

221

审稿时长

52 days

期刊介绍： Veterinary Microbiology is concerned with microbial (bacterial, fungal, viral) diseases of domesticated vertebrate animals (livestock, companion animals, fur-bearing animals, game, poultry, fish) that supply food, other useful products or companionship. In addition, Microbial diseases of wild animals living in captivity, or as members of the feral fauna will also be considered if the infections are of interest because of their interrelation with humans (zoonoses) and/or domestic animals. Studies of antimicrobial resistance are also included, provided that the results represent a substantial advance in knowledge. Authors are strongly encouraged to read - prior to submission - the Editorials (''Scope or cope'' and ''Scope or cope II'') published previously in the journal. The Editors reserve the right to suggest submission to another journal for those papers which they feel would be more appropriate for consideration by that journal. Original research papers of high quality and novelty on aspects of control, host response, molecular biology, pathogenesis, prevention, and treatment of microbial diseases of animals are published. Papers dealing primarily with immunology, epidemiology, molecular biology and antiviral or microbial agents will only be considered if they demonstrate a clear impact on a disease. Papers focusing solely on diagnostic techniques (such as another PCR protocol or ELISA) will not be published - focus should be on a microorganism and not on a particular technique. Papers only reporting microbial sequences, transcriptomics data, or proteomics data will not be considered unless the results represent a substantial advance in knowledge. Drug trial papers will be considered if they have general application or significance. Papers on the identification of microorganisms will also be considered, but detailed taxonomic studies do not fall within the scope of the journal. Case reports will not be published, unless they have general application or contain novel aspects. Papers of geographically limited interest, which repeat what had been established elsewhere will not be considered. The readership of the journal is global.