用于生物医学应用的植物生物质水凝胶。

IF 14.3 1区工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Trends in biotechnology Pub Date : 2024-10-08 DOI:10.1016/j.tibtech.2024.09.010

Tushuai Li, Wenxue Sun, Da Qian, Peng Wang, Xingyu Liu, Chengsheng He, Tong Chang, Guangfu Liao, Jie Zhang

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引用次数: 0

摘要

由植物提取的生物质制成的水凝胶在生物医学应用中越来越受欢迎，因为它们通常价格低廉、易于获得且具有生物相容性。事实证明，要为生物医学找到完美的植物生物质水凝胶，并能复制人体组织在结构、功能和性能方面的基本特征是非常困难的。在这篇综述中，我们总结了对这一主题的一些主要贡献，涵盖了基本观点以及由纤维素、半纤维素和木质素制成的不同生物质水凝胶。此外，我们还深入讨论了生物质水凝胶的生物安全性和毒性评估。最后，本综述还强调了有关生物质水凝胶在生物医学应用方面的重要科学辩论和主要障碍。

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Plant-derived biomass-based hydrogels for biomedical applications.

Hydrogels made of plant-derived biomass have gained popularity in biomedical applications because they are frequently affordable, readily available, and biocompatible. Finding the perfect plant-derived biomass-based hydrogels for biomedicine that can replicate essential characteristics of human tissues in regard to structure, function, and performance has proved to be difficult. In this review, we summarize some of the major contributions made to this topic, covering basic ideas and different biomass-based hydrogels made of cellulose, hemicellulose, and lignin. Also included is an in-depth discussion regarding the biosafety and toxicity assessments of biomass-based hydrogels. Finally, this review also highlights important scientific debates and major obstacles regarding biomass-based hydrogels for biomedical applications.

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来源期刊

Trends in biotechnology 工程技术-生物工程与应用微生物

CiteScore

28.60

自引率

1.20%

发文量

198

审稿时长

1 months

期刊介绍： Trends in Biotechnology publishes reviews and perspectives on the applied biological sciences, focusing on useful science applied to, derived from, or inspired by living systems. The major themes that TIBTECH is interested in include: Bioprocessing (biochemical engineering, applied enzymology, industrial biotechnology, biofuels, metabolic engineering) Omics (genome editing, single-cell technologies, bioinformatics, synthetic biology) Materials and devices (bionanotechnology, biomaterials, diagnostics/imaging/detection, soft robotics, biosensors/bioelectronics) Therapeutics (biofabrication, stem cells, tissue engineering and regenerative medicine, antibodies and other protein drugs, drug delivery) Agroenvironment (environmental engineering, bioremediation, genetically modified crops, sustainable development).