上丘：对古老进化结构的新认识

IF 4.8 2区医学 Q1 NEUROSCIENCES

Current Opinion in Neurobiology Pub Date : 2024-10-09 DOI:10.1016/j.conb.2024.102926

Teresa Guillamón-Vivancos, Fabrizio Favaloro, Francesco Dori, Guillermina López-Bendito

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引用次数: 0

摘要

上丘是位于中脑背侧的一个结构，其功能和连接性在不同物种间保持一致。上丘在进化过程中对生存起着至关重要的作用，可在受到外界刺激时触发快速定向和回避动作。在过去几年中，人们越来越认识到上丘不仅与脑干和脊髓，而且与几乎所有大脑结构都有广泛的联系，这重新点燃了人们对这一结构的兴趣，并揭示了它的新作用。在这篇综述中，我们将重点介绍在了解其细胞组成、连通性和功能方面取得的最新进展，尤其是细胞多样性和连通性是如何在发育过程中产生的，以及上丘最近在感觉回路出现过程中扮演的角色。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The superior colliculus: New insights into an evolutionarily ancient structure

The superior colliculus is a structure located in the dorsal midbrain with well conserved function and connectivity across species. Essential for survival, the superior colliculus has evolved to trigger rapid orientation and avoidance movements in response to external stimuli. The increasing recognition of the widespread connectivity of the superior colliculus, not only with brainstem and spinal cord, but also with virtually all brain structures, has rekindled the interest on this structure and revealed novel roles in the past few years. In this review, we focus on the most recent advancements in understanding its cellular composition, connectivity and function, with a particular focus on how the cellular diversity and connectivity arises during development, as well as on its recent role in the emergence of sensory circuits.

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来源期刊

Current Opinion in Neurobiology 医学-神经科学

CiteScore

11.10

自引率

1.80%

发文量

130

审稿时长

4-8 weeks

期刊介绍： Current Opinion in Neurobiology publishes short annotated reviews by leading experts on recent developments in the field of neurobiology. These experts write short reviews describing recent discoveries in this field (in the past 2-5 years), as well as highlighting select individual papers of particular significance. The journal is thus an important resource allowing researchers and educators to quickly gain an overview and rich understanding of complex and current issues in the field of Neurobiology. The journal takes a unique and valuable approach in focusing each special issue around a topic of scientific and/or societal interest, and then bringing together leading international experts studying that topic, embracing diverse methodologies and perspectives. Journal Content: The journal consists of 6 issues per year, covering 8 recurring topics every other year in the following categories: -Neurobiology of Disease- Neurobiology of Behavior- Cellular Neuroscience- Systems Neuroscience- Developmental Neuroscience- Neurobiology of Learning and Plasticity- Molecular Neuroscience- Computational Neuroscience