多发性骨髓瘤肾周髓质外疾病

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-10-10 DOI:10.1097/RLU.0000000000005520

Alex Koichi, Razvan Zemianschi, Fathima Fijula Palot Manzil, Joshua Eichhorn

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引用次数: 0

摘要

摘要：髓外疾病是多发性骨髓瘤的一种侵袭性形式，发生在骨骼之外，是一个不良的预后指标。髓外疾病最常累及皮肤、肌肉、胸膜、淋巴结、肝脏和中枢神经系统。髓外疾病很少累及肾脏或肾周。我们报告了 3 例髓质外疾病累及肾周的病例，18F-FDG PET/CT 经组织取样证实为浆细胞浸润。由于 18F-FDG 的排泄限制了肾脏的生理活动，因此在评估多发性骨髓瘤患者是否累及泌尿生殖系统时，必须仔细考虑，因为这可能与其他恶性肿瘤、出血或肾损伤相似。

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Perinephric Extramedullary Disease in Multiple Myeloma.

Abstract: Extramedullary disease represents an aggressive form of multiple myeloma occurring outside the skeleton and is a poor prognostic indicator. Extramedullary disease most commonly involves the skin, muscle, pleura, lymph nodes, liver, and central nervous system. Infrequently, extramedullary disease can involve the kidneys or perirenal space. We present 3 cases of perirenal involvement of extramedullary disease on 18 F-FDG PET/CT confirmed with tissue sampling as plasma cell infiltration. Within the limitation of physiologic activity in the kidneys due to 18 F-FDG excretion, close consideration is essential when evaluating multiple myeloma patients for genitourinary involvement as it can resemble other malignancies, hemorrhage, or renal injury.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.