尼日利亚中北部乔斯未接种疫苗的学龄儿童的风疹血清流行率。

IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Pan African Medical Journal Pub Date : 2024-09-02 eCollection Date: 2024-01-01 DOI:10.11604/pamj.2024.49.1.44172
Hyelshilni Samuel Waziri, Fatima Giwa, Adebola Tolulope Olayinka, Ndadilnasiya Endie Waziri, Clement Koeloengan Da'am, Yahaya Mohammed, Patrick Nguku, Samuel Abednego Dahal, Ugochukwu Nwokoro, Joseph Nakah, Yadang Dasohot Maktep, Ahmed Olowo-Okere
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引用次数: 0

摘要

导言:风疹对公共卫生构成重大威胁,尤其是在发展中国家,先天性风疹仍是一个可预防的问题。这项横断面研究调查了 2016 年 5 月至 9 月期间尼日利亚乔斯市 10 岁及以下儿童的风疹血清流行率。方法:采用多阶段抽样方法,在该市各学校招募符合条件且未接种风疹病毒疫苗并同意参与研究的参与者。使用酶联免疫吸附试验(ELISA)从参与者采集的洗脱血清中检测风疹特异性 IgG 和 IgM 抗体。结果:在接受调查的 405 名参与者中,336 人(82.96%)的风疹 IgG 检测呈阳性,9 人(2.22%)的风疹 IgM 检测呈阳性。年龄≥5 岁和未接受过西方教育等因素与风疹血清阳性有显著关联。结论:本研究强调了风疹 IgG 和 IgM 抗体在尼日利亚乔斯 10 岁及以下儿童中的血清流行率。风疹血清阳性率与年龄≥5 岁和缺乏西方教育等因素之间存在明显关联,这突出表明有必要实施有效的风疹疫苗接种计划,以预防先天性风疹综合症(CRS)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rubella seroprevalence among unvaccinated school-aged children in Jos, North Central, Nigeria.

Introduction: rubella poses a significant public health threat, particularly in developing countries, where congenital rubella remains a preventable concern. This cross-sectional study examined rubella seroprevalence among children aged 10 and under from May to September 2016 in Jos, Nigeria.

Methods: using a multistage sampling method, eligible participants who had not been vaccinated against the rubella virus and consented to participate in the study were recruited across schools in the city. Rubella-specific IgG and IgM antibodies were detected from eluted serum collected from the participants using the enzyme-linked immunosorbent assay (ELISA). Data analysis and visualization was done using the R software version 4.3.1.

Results: of the 405 participants investigated in this study, 336 (82.96%) tested positive for rubella IgG, while 9 (2.22%) tested positive for rubella IgM. Factors such as age ≥ 5 years and lack of Western education showed significant associations with rubella seropositivity.

Conclusion: this study highlights the seroprevalence of rubella IgG and IgM antibodies among children aged 10 and under in Jos, Nigeria. The significant associations between rubella seropositivity and factors such as age ≥ 5 years and lack of Western education underscore the necessity for an effective rubella vaccination program to prevent congenital rubella syndrome (CRS).

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来源期刊
Pan African Medical Journal
Pan African Medical Journal PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
1.80
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0.00%
发文量
691
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