[造血疾病患者的生育能力保护]。

Yuma Tada
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引用次数: 0

摘要

过去几十年来,造血疾病的预后一直在改善,因此需要采取措施满足患者的生育愿望,以提高幸存者的生活质量。在日本,日本生育力保存协会率先制定了指导方针,建立了国家登记处和全国统一的补贴制度。在考虑对造血疾病患者进行生育力保存时,肿瘤科和辅助生育科之间必须开展跨学科合作,以解决造血疾病特有的问题,如发病与开始治疗之间的时间间隔短、与生育力保存治疗相关的并发症(如出血或卵巢过度刺激综合征)以及采集的组织被造血肿瘤细胞污染等。本文概述了造血疾病患者生育力保存的基本概念,以及最近为慢性骨髓性白血病妇女制定的策略。本文还将分享一些创新治疗方法,在生育力保存治疗可能具有挑战性的情况下,可以考虑采用这些方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Fertility preservation in patients with hematopoietic diseases].

The prognosis of hematopoietic diseases has been improving over the past several decades, and measures to fulfill patients' wishes to have children are needed to improve survivors' quality of life. In Japan, the Japan Society for Fertility Preservation has taken the lead in developing guidelines, a national registry, and a nationwide uniform subsidy system. When considering fertility preservation in patients with hematopoietic diseases, interdisciplinary collaboration between oncology and onco-fertility is necessary to solve problems specific to hematopoietic diseases, such as the short time window between the onset of disease and the start of treatment, complications associated with fertility preservation treatment such as bleeding or ovarian hyperstimulation syndrome, and contamination of collected tissue with hematopoietic tumor cells. This article outlines the basic concept of fertility preservation in patients with hematopoietic diseases and recently established strategies for women with chronic myelogenous leukemia. It will also share some treatment innovations that can be considered in cases when fertility preservation treatment may be challenging.

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