跨越距离的交流--细胞外囊泡的生物功能。

IF 4.1 3区医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biomedical Journal Pub Date : 2024-10-01 DOI:10.1016/j.bj.2024.100792

Aila Akosua Kattner

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引用次数: 0

摘要

本期《生物医学杂志》的特别栏目介绍了细胞外囊泡 (EVs)，涵盖了它们在神经系统疾病、病毒感染、同种异体器官排斥和耐受中的作用，以及 EVs 的生物分布。两篇文章探讨了帕金森病的发病机制，重点是白质和外泌体。本期杂志还探讨了多瘤病毒诱导的肾移植移植物损伤，提出了作为川崎病诊断生物标记物的miRNA特征，讨论了神经门控和相关的脑电波改变，并进一步阐明了肠道微生物群与免疫检查点抑制剂之间的关系。此外，还重申了治疗药物监测的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Communicating across distances – Biological functions of extracellular vesicles

This issue of the Biomedical Journal features a special section on extracellular vesicles (EVs), covering their role in neurological diseases, viral infections, trogocytosis, allogeneic organ rejection and tolerance, as well as EV biodistribution. Two articles explore the mechanisms of Parkinson's disease, focusing on white matter and exosomes. This journal issue also examines polyomavirus-induced damage in renal transplant grafts, proposes a miRNA signature as a diagnostic biomarker for Kawasaki disease, discusses neural gating and associated brain wave alterations, and further clarifies the relationship between gut microbiota and immune checkpoint inhibitors. Additionally, the importance of therapeutic drug monitoring is reaffirmed.

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来源期刊

Biomedical Journal Medicine-General Medicine

CiteScore

11.60

自引率

1.80%

发文量

128

审稿时长

42 days

期刊介绍： Biomedical Journal publishes 6 peer-reviewed issues per year in all fields of clinical and biomedical sciences for an internationally diverse authorship. Unlike most open access journals, which are free to readers but not authors, Biomedical Journal does not charge for subscription, submission, processing or publication of manuscripts, nor for color reproduction of photographs. Clinical studies, accounts of clinical trials, biomarker studies, and characterization of human pathogens are within the scope of the journal, as well as basic studies in model species such as Escherichia coli, Caenorhabditis elegans, Drosophila melanogaster, and Mus musculus revealing the function of molecules, cells, and tissues relevant for human health. However, articles on other species can be published if they contribute to our understanding of basic mechanisms of biology. A highly-cited international editorial board assures timely publication of manuscripts. Reviews on recent progress in biomedical sciences are commissioned by the editors.