用于微混合的新型高灵敏度测试反应：草酸乙酯的酸碱中和与碱性水解反应

IF 3.5 3区工程技术 Q2 ENGINEERING, CHEMICAL

AIChE Journal Pub Date : 2024-10-01 DOI:10.1002/aic.18615

Dingwang Huang, Xiaoxia Duan, Xin Feng, Guilong Wang, Weipeng Zhang, Jie Chen, Zai-Sha Mao, Chao Yang

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引用次数: 0

摘要

化学反应器中的微混合可通过对混合敏感的测试反应来表征。本研究提出了一对新的平行竞争反应，包括酸碱中和和草酸二乙酯水解。它原理清晰，对微混合灵敏度高，定量准确，操作简单。停流光谱的测量结果表明，草酸二乙酯的碱性水解遵循二阶动力学，速率常数符合阿伦尼乌斯方程 k2 = 2.331 × 108 exp(-26.92 × 103/RT) (L/mol/s)。在选定的浓度组合下，估计水解半衰期约为 3 × 10-4 s，这为在强湍流环境中进行微混合评估提供了显著优势。在同一搅拌槽中，新试验反应的临界进料时间比 Villermaux-Dushman 反应的临界进料时间短。总之，这项工作为筛选其他需要快速水解的酯类以构建更多的微混合试验反应提供了实用的思路。

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A novel highly sensitive test reaction for micromixing: Acid-base neutralization and alkaline hydrolysis of ethyl oxalate

Micromixing in chemical reactors can be characterized through test reactions that are sensitive to mixing. A new pair of parallel competitive reactions, including acid–base neutralization and diethyl oxalate hydrolysis, is proposed in this work. It has clear principles and high sensitivity to micromixing with quantitative accuracy and operational simplicity. The measurement results obtained from stopped-flow spectra show that the alkaline hydrolysis of diethyl oxalate follows second-order kinetics, and the rate constant conforms to the Arrhenius equation k₂ = 2.331 × 10⁸ exp(−26.92 × 10³/RT) (L/mol/s). The estimated half-life of hydrolysis is approximately 3 × 10⁻⁴ s under the selected concentration combinations, which provides significant advantages for the micromixing assessment in the strong turbulent fluid environment. In the same stirred tank, the critical feed time of new test reaction is shorter than that of the Villermaux–Dushman reaction. Overall, this work provides practical ideas for screening other desired esters for fast hydrolysis to construct more test reactions for micromixing.

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来源期刊

AIChE Journal 工程技术-工程：化工

CiteScore

7.10

自引率

10.80%

发文量

411

审稿时长

3.6 months

期刊介绍： The AIChE Journal is the premier research monthly in chemical engineering and related fields. This peer-reviewed and broad-based journal reports on the most important and latest technological advances in core areas of chemical engineering as well as in other relevant engineering disciplines. To keep abreast with the progressive outlook of the profession, the Journal has been expanding the scope of its editorial contents to include such fast developing areas as biotechnology, electrochemical engineering, and environmental engineering. The AIChE Journal is indeed the global communications vehicle for the world-renowned researchers to exchange top-notch research findings with one another. Subscribing to the AIChE Journal is like having immediate access to nine topical journals in the field. Articles are categorized according to the following topical areas: Biomolecular Engineering, Bioengineering, Biochemicals, Biofuels, and Food Inorganic Materials: Synthesis and Processing Particle Technology and Fluidization Process Systems Engineering Reaction Engineering, Kinetics and Catalysis Separations: Materials, Devices and Processes Soft Materials: Synthesis, Processing and Products Thermodynamics and Molecular-Scale Phenomena Transport Phenomena and Fluid Mechanics.