{"title":"关于本质性震颤的六个神话和误解。","authors":"Elan D Louis","doi":"10.5334/tohm.948","DOIUrl":null,"url":null,"abstract":"<p><p>There are myths and misperceptions about most human diseases, and neurological diseases are no exception. In many instances, myths and misconceptions reflect what is no more than the collective failure of the field to catch up with the state of the science in that field. Hence, one may perhaps refer to these as \"lags\" rather than myths. As the field of medicine attempts to be evidence-based, it is best to remain true to published data and the state of the science. In this paper, I review six myths and misconceptions about ET. Myth 1 relates to the natural history and prognosis of ET. Myths 2 and 3 relate to the biological basis of ET, whereas myths 4 and 5 relate to the expression of the core clinical feature of ET. Finally, myth 6 focuses on the issue of disease classification. The myths are as follows: <i>Myth 1:</i> \"ET is not associated with a shorter life expectancy\". <i>Myth 2:</i> \"The pathophysiology of ET remains unclear\". <i>Myth 3:</i> \"There have also been studies that do not show any cerebellar degeneration\". <i>Myth 4:</i> \"ET is a postural or a kinetic tremor\". <i>Myth 5:</i> \"Action tremor in ET is usually bilateral and symmetric\". <i>Myth 6:</i> \"ET plus\". As neurologists, we are not ignorant of feedback loops. A regular review of facts should help to frame one's output. As such, one's formulations and output will be firmly grounded in data.</p>","PeriodicalId":23317,"journal":{"name":"Tremor and Other Hyperkinetic Movements","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11428667/pdf/","citationCount":"0","resultStr":"{\"title\":\"Six Myths and Misconceptions about Essential Tremor.\",\"authors\":\"Elan D Louis\",\"doi\":\"10.5334/tohm.948\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>There are myths and misperceptions about most human diseases, and neurological diseases are no exception. In many instances, myths and misconceptions reflect what is no more than the collective failure of the field to catch up with the state of the science in that field. Hence, one may perhaps refer to these as \\\"lags\\\" rather than myths. As the field of medicine attempts to be evidence-based, it is best to remain true to published data and the state of the science. In this paper, I review six myths and misconceptions about ET. Myth 1 relates to the natural history and prognosis of ET. Myths 2 and 3 relate to the biological basis of ET, whereas myths 4 and 5 relate to the expression of the core clinical feature of ET. Finally, myth 6 focuses on the issue of disease classification. The myths are as follows: <i>Myth 1:</i> \\\"ET is not associated with a shorter life expectancy\\\". <i>Myth 2:</i> \\\"The pathophysiology of ET remains unclear\\\". <i>Myth 3:</i> \\\"There have also been studies that do not show any cerebellar degeneration\\\". <i>Myth 4:</i> \\\"ET is a postural or a kinetic tremor\\\". <i>Myth 5:</i> \\\"Action tremor in ET is usually bilateral and symmetric\\\". <i>Myth 6:</i> \\\"ET plus\\\". As neurologists, we are not ignorant of feedback loops. A regular review of facts should help to frame one's output. As such, one's formulations and output will be firmly grounded in data.</p>\",\"PeriodicalId\":23317,\"journal\":{\"name\":\"Tremor and Other Hyperkinetic Movements\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2024-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11428667/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tremor and Other Hyperkinetic Movements\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5334/tohm.948\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tremor and Other Hyperkinetic Movements","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5334/tohm.948","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
大多数人类疾病都存在神话和误解,神经系统疾病也不例外。在许多情况下,神话和误解反映的不过是该领域的集体失败,未能赶上该领域的科学发展水平。因此,我们或许可以将其称为 "滞后",而不是神话。由于医学领域试图以证据为基础,因此最好忠实于已发表的数据和科学现状。在本文中,我将回顾有关 ET 的六个神话和误解。误区 1 与 ET 的自然病史和预后有关。误区 2 和 3 与 ET 的生物学基础有关,而误区 4 和 5 则与 ET 核心临床特征的表现有关。最后,误区 6 主要涉及疾病分类问题。这些误解如下误区 1:"ET 与预期寿命缩短无关"。误区 2:"ET 的病理生理学尚不清楚"。误区 3:"也有一些研究没有显示任何小脑变性"。误区 4:"ET 是一种姿势性或运动性震颤"。误区 5:"ET 的动作性震颤通常是双侧对称的"。误区 6:"ET 加"。作为神经科医生,我们并非对反馈回路一无所知。对事实的定期回顾应有助于确定自己的产出。因此,我们的表述和结果将以数据为坚实基础。
Six Myths and Misconceptions about Essential Tremor.
There are myths and misperceptions about most human diseases, and neurological diseases are no exception. In many instances, myths and misconceptions reflect what is no more than the collective failure of the field to catch up with the state of the science in that field. Hence, one may perhaps refer to these as "lags" rather than myths. As the field of medicine attempts to be evidence-based, it is best to remain true to published data and the state of the science. In this paper, I review six myths and misconceptions about ET. Myth 1 relates to the natural history and prognosis of ET. Myths 2 and 3 relate to the biological basis of ET, whereas myths 4 and 5 relate to the expression of the core clinical feature of ET. Finally, myth 6 focuses on the issue of disease classification. The myths are as follows: Myth 1: "ET is not associated with a shorter life expectancy". Myth 2: "The pathophysiology of ET remains unclear". Myth 3: "There have also been studies that do not show any cerebellar degeneration". Myth 4: "ET is a postural or a kinetic tremor". Myth 5: "Action tremor in ET is usually bilateral and symmetric". Myth 6: "ET plus". As neurologists, we are not ignorant of feedback loops. A regular review of facts should help to frame one's output. As such, one's formulations and output will be firmly grounded in data.