从偃麦草种子中提取的油的植物化学筛选和理化分析,以及抗氧化活性的测定。

IF 0.7 4区 医学 Q4 PHARMACOLOGY & PHARMACY
Muhammad Najeeb Ullah, Ijaz Ali, Sana Hanif, Muhammad Ali Syed, Muhammad Talha, Muhammad Ahsan Samran, Arslan Haider, Muhammad Huraira
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引用次数: 0

摘要

茜草是一种具有民族药用价值的植物,属于茜草科,传统上用于治疗各种疾病。随着全球对草药疗法兴趣的增加,必须对植物化学成分进行科学验证,以确保其治疗效用和安全性。本研究旨在全面分析蚕豆种子油的植物化学成分,为其药用价值提供证据。采用推荐的标准索氏提取法从种子中分离出油。对其化学成分、理化参数和抗氧化潜力进行了表征。气相色谱-质谱分析显示了 31 种不同的植物成分,包括重要的萜类、酮类、酯类、醇类、脂肪族酸类和其他少量化合物,这些化合物具有广泛的医药用途。经鉴定,具有营养和治疗功效的主要不饱和脂肪酸包括油酸、亚油酸、棕榈油酸、花生四烯酸和二十二碳六烯酸。67.832g I/100g 的高碘值表明不饱和程度很高。虽然 DPPH 试验显示出的抗氧化活性极低,但其中的多种生物活性成分赋予了偃麦草籽油重要的药理作用。通过提供深入的植物化学见解,这项研究工作验证了这种油的传统和其他药用价值,可进一步探索其在民族医药方面的新用途。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Phytochemical screening and physicochemical analysis of oil extracted from seeds of Bombax ceiba and determination of antioxidant activity.

Bombax ceiba, an ethnomedically useful plant belonging to the Bombacaceae family, is traditionally used to treat various ailments. With the increase of interest in herbal remedies globally, it is imperative to scientifically validate the phytochemical profiling to ensure therapeutic utility and safety. The present study was designed to comprehensively analyze the phytochemical composition of Bombax ceiba seeds oil to provide evidence for its medicinal uses. The recommended standard Soxhlet extraction method was used to isolate the oil from the seeds. Its chemical profile, physicochemical parameters and antioxidant potential were characterized. The GC-MS analysis revealed the presence of 31 diverse phytoconstituents including vital terpenoids, ketones, esters, alcohols, aliphatic acids, and other compounds in minor quantities which are known to possess wide pharmaceutical applications. The key unsaturated fatty acids identified with nutritional and therapeutic benefits were oleic, linoleic, palmitoleic, arachidonic and docosahexaenoic acids. The high iodine value of 67.832g I/100g indicates a high degree of unsaturation. Although the DPPH assay showed minimal antioxidant activity, the myriad of bioactive components confers significant pharmacological utility to Bombax ceiba seeds oil. By providing in-depth phytochemical insights, this research work validates this oil's traditional and other medicinal uses, which can be further explored for newer ethnomedicine development.

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来源期刊
CiteScore
1.40
自引率
12.50%
发文量
211
审稿时长
4.5 months
期刊介绍: Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013. PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.
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