抗真菌时代的药房对患者的指导。

IF 4.1 2区 医学 Q1 DERMATOLOGY
Mycoses Pub Date : 2024-09-01 DOI:10.1111/myc.13802
Catja Alcoat, Elisabeth M M Christensen, Gregor B E Jemec, Kenneth Skov, Ditte M L Saunte
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引用次数: 0

摘要

背景:足癣是最常见的浅表真菌感染之一。最初的抗真菌治疗通常是通过非处方药(OTC)获得的,事先并未咨询医生:最近,在丹麦和全球范围内,抗真菌药物特比萘芬的耐药性不断增加,因此,我们有兴趣评估丹麦药店如何为患有足癣的顾客提供建议:随机抽取了 100 家丹麦药店,并对每家药店的一名员工进行了访谈。方法:随机抽取 100 家丹麦药房,每家药房派一名员工接受访谈,访谈采用结构化问题指南,并可添加进一步评论:结果:对 94 家药房进行了访谈。有 6 家药店从未回复。99%的药店员工建议将特比萘芬标准剂量或特比萘芬一次性皮肤溶液(Lamisil Once (R))作为一线治疗药物。当足癣复发(93%)或治疗时间超过两周(77%)时,建议顾客就医。大多数药房员工(88%)对抗真菌耐药性一无所知:结论:只有少数药房员工了解当前的抗真菌耐药性问题,大多数员工建议顾客使用非处方外用特比萘芬开始治疗。新出现的抗真菌药物耐药性问题需要引起重视,以便为患有足癣的顾客提供有效的治疗,并防止抗真菌药物耐药性在社会上进一步蔓延。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pharmacies Counselling of Patients in the Era of Antifungal Resistance.

Background: Tinea pedis is one of the most prevalent superficial fungal infections. Initial antifungal treatment is often acquired over-the-counter (OTC) without previous consultation with a physician.

Objective: Lately, increasing antifungal terbinafine resistance has been documented in Denmark and globally and it is therefore of interest to assess how Danish pharmacies advise customers with tinea pedis.

Methods: One hundred Danish pharmacies were randomly selected and an employee interviewed from each. A structured question guide was followed, with the possibility to add further comments.

Results: Interviews of 94 pharmacies were conducted. Six pharmacies never replied. Terbinafine as standard dose or cutaneous solution terbinafine one time application (Lamisil Once (R)) were recommended by 99% of the pharmacy employees as first-line treatment. The customer was advised to seek medical attention when tinea pedis was recurring (93%), or when treatment duration was > 2 weeks (77%). The majority (88%) of the pharmacy employees had no knowledge about antifungal resistance.

Conclusion: Only few pharmacy employees were aware of the current problem of antifungal resistance and the majority advised costumers to initiate treatment using OTC topical terbinafine. The problem of emerging antifungal resistance requires attention in order to provide customers with tinea pedis effective treatment and prevent further societal spread of resistance to antifungals.

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来源期刊
Mycoses
Mycoses 医学-皮肤病学
CiteScore
10.00
自引率
8.20%
发文量
143
审稿时长
6-12 weeks
期刊介绍: The journal Mycoses provides an international forum for original papers in English on the pathogenesis, diagnosis, therapy, prophylaxis, and epidemiology of fungal infectious diseases in humans as well as on the biology of pathogenic fungi. Medical mycology as part of medical microbiology is advancing rapidly. Effective therapeutic strategies are already available in chemotherapy and are being further developed. Their application requires reliable laboratory diagnostic techniques, which, in turn, result from mycological basic research. Opportunistic mycoses vary greatly in their clinical and pathological symptoms, because the underlying disease of a patient at risk decisively determines their symptomatology and progress. The journal Mycoses is therefore of interest to scientists in fundamental mycological research, mycological laboratory diagnosticians and clinicians interested in fungal infections.
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