Ad26.COV2.S COVID-19 疫苗在 16-17 岁青少年中的安全性和免疫原性。

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Journal of the Pediatric Infectious Diseases Society Pub Date : 2024-11-27 DOI:10.1093/jpids/piae098

Javier Ruiz-Guiñazú, Mathieu Le Gars, Vicky Cárdenas, Nathalie Vaissière, Jerald Sadoff, Carla Truyers, Jenny Hendriks, Gert Scheper, A Marit de Groot, Frank Struyf, Hanneke Schuitemaker, Macaya Douoguih

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引用次数: 0

摘要

2.5 × 1010 vp Ad26.COV2.S能在接种 6 个月的青少年中引起强有力的SARS-CoV-2特异性抗体反应，其安全性和反应原性均可接受。与接种 5 × 1010 vp Ad26.COV2.S 的成人相比，青少年的抗体水平更高，尽管接种的剂量更低。

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Ad26.COV2.S COVID-19 Vaccine Safety And Immunogenicity in Adolescents 16-17 Years of Age.

2.5 × 1010 vp Ad26.COV2.S elicited robust SARS-CoV-2-specific antibody responses in adolescents through 6 months, with acceptable safety and reactogenicity profiles. Compared with adults immunized with 5 × 1010 vp Ad26.COV2.S, adolescents had higher antibody levels, despite being vaccinated with a lower dose.

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来源期刊

Journal of the Pediatric Infectious Diseases Society Medicine-Pediatrics, Perinatology and Child Health

CiteScore

6.70

自引率

0.00%

发文量

179

期刊介绍： The Journal of the Pediatric Infectious Diseases Society (JPIDS), the official journal of the Pediatric Infectious Diseases Society, is dedicated to perinatal, childhood, and adolescent infectious diseases. The journal is a high-quality source of original research articles, clinical trial reports, guidelines, and topical reviews, with particular attention to the interests and needs of the global pediatric infectious diseases communities.