调查美国儿科内分泌专家在常规脑磁共振成像中使用钆基造影剂评估孤立性生长激素缺乏症的现行做法。

IF 2.6 3区医学 Q3 ENDOCRINOLOGY & METABOLISM

Hormone Research in Paediatrics Pub Date : 2024-09-30 DOI:10.1159/000541661

Daniel Mak, Emily Breidbart, Shilpa Mehta, Brenda Kohn

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引用次数: 0

摘要

简介：这项调查研究了儿科内分泌学会（PES）会员针对孤立性GHD进行脑部核磁共振成像的做法，重点是钆基造影剂（GBCA）与非造影剂核磁共振成像：我们向 1553 名儿科内分泌协会会员发放了一份包含 15 个问题的调查问卷，调查内容包括 GBCA 的使用情况、非造影剂的使用情况以及对钆滞留的认识：85%的受访者会定期为孤立的 GHD 患者进行脑部 MRI 检查，其中 60% 使用 GBCA。大多数受访者可以使用高分辨率非对比成像，但有 54% 的受访者不了解钆潴留风险：结论：高分辨率非造影剂磁共振成像具有诊断效果，这表明在临床实践中，孤立性 GHD 的诊断将不再使用 GBCAs。这项调查为更新评估孤立性 GHD 的 PES 指南提供了依据。

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Surveying Current Practices in the Use of Gadolinium-Based Contrast Agents for Routine Brain Magnetic Resonance Imaging in the Evaluation of Isolated Growth Hormone Deficiency among US Pediatric Endocrinologists.

Introduction: This survey investigates brain MRI practices for isolated GHD among Pediatric Endocrine Society (PES) members, focusing on gadolinium-based contrast agents (GBCAs) versus non-contrast MRI.

Methods: A 15-question survey was distributed to 1,553 PES members, capturing data on GBCA usage, non-contrast imaging access, and awareness of gadolinium retention.

Results: A total of 85% of respondents routinely order brain MRIs for isolated GHD, with 60% using GBCAs. Most respondents have access to high-resolution non-contrast imaging, though 54% are unaware of gadolinium retention risks.

Conclusion: High-resolution non-contrast MRI demonstrates diagnostic efficacy, suggesting a shift away from GBCAs in clinic practice for isolated GHD. The survey forms the basis to update PES guidelines in the evaluation of isolated GHD.

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来源期刊

Hormone Research in Paediatrics ENDOCRINOLOGY & METABOLISM-PEDIATRICS

CiteScore

4.90

自引率

6.20%

发文量

审稿时长

4-8 weeks

期刊介绍： The mission of ''Hormone Research in Paediatrics'' is to improve the care of children with endocrine disorders by promoting basic and clinical knowledge. The journal facilitates the dissemination of information through original papers, mini reviews, clinical guidelines and papers on novel insights from clinical practice. Periodic editorials from outstanding paediatric endocrinologists address the main published novelties by critically reviewing the major strengths and weaknesses of the studies.