James E Bogan, Robert J Ossiboff, April L Childress, James F X Wellehan, Alexandra K Mason
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引用次数: 0
摘要
一个原产于野外的东部蓝靛蛇（EISs，Drymarchon couperi）繁殖群受到了胃隐孢子虫病的影响，该繁殖群是重新引入计划的一部分。胃隐孢子虫病是有鳞类动物的一种隐性疾病，由一种无孢原生动物蛇隐孢子虫引起。病毒合并感染被认为可能是导致疾病进展的免疫抑制剂，腺病毒和雷诺病毒在其他蛇类物种的合并感染中也被认为导致了胃隐孢子虫病的进展。对繁殖群中蛇毒阳性和蛇毒阴性的 EIS 进行了腺病毒和再病毒的分子（PCR）筛查。在采集的 EIS 中未检测到再病毒。经评估，11/68（16.2%）个 EIS 存在腺病毒，蛇尾蝇阳性 EIS 与蛇尾蝇阴性 EIS 之间无显著差异（p = 0.196）。C.serpentis阳性EIS的寿命（p = 0.191）和存活率（p = 0.823）与腺病毒状态无明显差异。这些结果表明，本研究中发现的腺病毒不会导致 EIS 胃隐孢子虫病的形成或发展。
Evaluating the Effects of Viruses on Eastern Indigo Snakes (Drymarchon couperi) with Gastric Cryptosporidiosis.
A breeding colony of wild-origin eastern indigo snakes (EISs, Drymarchon couperi) that is part of a reintroduction program has been impacted by gastric cryptosporidiosis. Gastric cryptosporidiosis is an insidious disease of squamates caused by an apicomplexan protozoan, Cryptosporidium serpentis. Viral coinfections have been implicated as possible immunosuppressant agents that allow for disease progression and both adenovirus and reovirus have been implicated in allowing for the progression of gastric cryptosporidiosis during coinfection in other snake species. Molecular (PCR) screening for adenoviruses and reoviruses was performed for both C. serpentis-positive and C. serpentis-negative EIS within the breeding colony. No reoviruses were detected in the collection. Adenoviruses were present in 11/68 (16.2%) EISs evaluated, and there was no significant difference between C. serpentis-positive and C. serpentis-negative EISs (p = 0.196). There was no significant difference in adenovirus status between C. serpentis-positive EISs' lifespan (p = 0.191) or survival rates (p = 0.823). These findings suggest that the presence of the adenoviruses found in this study does not contribute to the formation or progression of gastric cryptosporidiosis in EISs.
期刊介绍：
Viruses (ISSN 1999-4915) is an open access journal which provides an advanced forum for studies of viruses. It publishes reviews, regular research papers, communications, conference reports and short notes. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. We also encourage the publication of timely reviews and commentaries on topics of interest to the virology community and feature highlights from the virology literature in the ''News and Views'' section. Electronic files or software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.
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