激光针灸对久坐人群代谢功能的影响:双盲随机临床试验。

IF 1.8 Q2 SURGERY
Henrique Manoel de Araujo Martins Filho, Melissa de Almeida Melo Maciel Mangueira, Luciano Gonçalves da Nóbrega, Ozimo Pereira Gama Filho, Osmar Pinto Neto, Nilton Maciel Mangueira, Renato Amaro Zângaro
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引用次数: 0

摘要

背景介绍激光针灸可调节能量流动,恢复体液代谢。研究目的评估激光针灸方案(LAP)对久坐人群肝肾代谢的影响。方法:采用纵向、双盲、对照组和对照组方法:纵向、双盲、随机临床试验,29 名参与者均为成年人,男女不限,久坐不动,无代谢性疾病,分为对照组和激光组。根据《2010 年针灸临床试验干预措施报告标准》,10 次激光照射(波长为 660 nm ±10 nm,功率为 100 mW。照射尖端直径为 5 毫米,相当于 0.19 平方厘米的面积,总功率密度为 0.52 瓦/平方厘米,考虑到照射时间为 90 秒,应用的能量密度为 47.在新陈代谢功能穴位(LR3、SP6、ST36 和 LI4)上进行了 "穴位刺激",并采集了血样,以检测空腹血糖、血脂(高密度脂蛋白、低密度脂蛋白、总胆固醇和甘油三酯)、肝功能(AST/GOT 和 ALT/GPT)和肾功能(血清肌酐和尿素)。采用重复测量方差分析(ANOVA)和经 Bonferroni 校正的事后比较来比较组间和时间间的统计学差异,以 p < 0.05 为零假设。结果激光刺激了血清脂质概况值和肝肾功能的变化。低密度脂蛋白("坏 "胆固醇)从干预前的 105.75 ± 32.83 mg/dL 降至干预后的 84.32 ± 18.38 mg/dL,降幅明显(p = 0.014),这与心脏保护功能有关。在降低肌酐(0.86 ± 0.12 mg/dL 至 0.75 ± 0.12 mg/dL)和 AST/GOT 酶(33.73 ± 12.95 U/L 至 20.80 ± 4.99 U/L, p = 0.002)方面也观察到了积极的重大影响(p = 0.035)。结论将 LAP 应用于基础代谢穴位可促进血脂(低密度脂蛋白)、肝脏(AST/GOT)和肾脏(肌酐)功能的主要指标发生积极的代谢变化,有助于控制心血管疾病的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of Laser Acupuncture on Metabolic Functions of Sedentary People: A Double-Blind Randomized Clinical Trial.

Background: Laser acupuncture regulates energy flow and restores body fluid metabolism. Objective: To evaluate the effects of the laser acupuncture protocol (LAP) on hepatic and renal metabolism in sedentary people. Methods: Longitudinal, double-blind, and randomized clinical trial with 29 participants, adults, both sexes, sedentary, without pre-existing metabolic diseases, subdivided into control and laser groups. Based on the STandards for Reporting Interventions in Clinical Trials of Acupuncture 2010 guidelines, 10 laser applications (660 nm ±10 nm wavelength, 100 mW power. The irradiation tip has a diameter of 5 mm, which corresponds to an area of 0.19 cm2, totaling a power density of 0.52 W/cm2 and considering the irradiation time of 90 s, the energy density applied was 47.3 J/cm2) were performed on the acupoints of metabolic functions (LR3, SP6, ST36, and LI4) and blood samples were collected for fasting glycemia, lipid profile (HDL, LDL, total cholesterol, and triglycerides), liver function (AST/GOT and ALT/GPT), and renal function (serum creatinine and urea). A repeated measures analysis of variance (ANOVA) with Bonferroni corrected post hoc comparisons was applied to compare statistical differences between groups and times, adopting p < 0.05 as the null hypothesis. Results: The laser stimulated changes in serum lipid profile values and renal and hepatic functions. There was a significant (p = 0.014) reduction in LDL ("bad" cholesterol) from 105.75 ± 32.83 pre- to 84.32 ± 18.38 mg/dL postintervention, associated with cardioprotective function. Positive significant (p = 0.035) impacts were also observed in the reduction of creatinine (0.86 ± 0.12 mg/dL to 0.75 ± 0.12 mg/dL) and the enzyme AST/GOT (33.73 ± 12.95 U/L to 20.80 ± 4.99 U/L, p = 0.002). Conclusion: LAP applied to basal metabolism acupoints promoted positive metabolic changes in the lipid profile (LDL), and in main markers of the liver (AST/GOT) and kidney (creatinine) functions, contributing to risk control of cardiovascular diseases.

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期刊介绍: Photobiomodulation, Photomedicine, and Laser Surgery Editor-in-Chief: Michael R Hamblin, PhD Co-Editor-in-Chief: Heidi Abrahamse, PhD
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