BCl3 催化炔/烯的 Z 选择性分子内氯氨基甲酰化反应

IF 4.6 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Chemistry Frontiers Pub Date : 2024-09-28 DOI:10.1039/D4QO01487A

Zhantao Yang, Linlin Chen, Yuhang Zhao, Qianhui Chen, Wanjun Zhao, Linfei Li, Boxuan Zhang, Hua Xie, Xiangtao Kong and Chun-Hua Yang

{"title":"BCl3 催化炔/烯的 Z 选择性分子内氯氨基甲酰化反应","authors":"Zhantao Yang, Linlin Chen, Yuhang Zhao, Qianhui Chen, Wanjun Zhao, Linfei Li, Boxuan Zhang, Hua Xie, Xiangtao Kong and Chun-Hua Yang","doi":"10.1039/D4QO01487A","DOIUrl":null,"url":null,"abstract":"A metal-free stereoselective intramolecular chlorocarbamoylation of alkynes/allenes driven by BCl3 was described, which provides a general and practical method for constructing versatile and chlorinated methylene lactams or tetrahydroisoquinolinones with (Z) geometry at the double bond, featuring a stereochemically defined tetrasubstituted chloroethene.","PeriodicalId":97,"journal":{"name":"Organic Chemistry Frontiers","volume":" 23","pages":" 6678-6683"},"PeriodicalIF":4.6000,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"BCl3 catalyzed Z-selective intramolecular chlorocarbamoylation of alkynes/allenes†\",\"authors\":\"Zhantao Yang, Linlin Chen, Yuhang Zhao, Qianhui Chen, Wanjun Zhao, Linfei Li, Boxuan Zhang, Hua Xie, Xiangtao Kong and Chun-Hua Yang\",\"doi\":\"10.1039/D4QO01487A\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A metal-free stereoselective intramolecular chlorocarbamoylation of alkynes/allenes driven by BCl3 was described, which provides a general and practical method for constructing versatile and chlorinated methylene lactams or tetrahydroisoquinolinones with (Z) geometry at the double bond, featuring a stereochemically defined tetrasubstituted chloroethene.\",\"PeriodicalId\":97,\"journal\":{\"name\":\"Organic Chemistry Frontiers\",\"volume\":\" 23\",\"pages\":\" 6678-6683\"},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2024-09-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Organic Chemistry Frontiers\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://pubs.rsc.org/en/content/articlelanding/2024/qo/d4qo01487a\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic Chemistry Frontiers","FirstCategoryId":"92","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2024/qo/d4qo01487a","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}

引用次数: 0

摘要

该研究描述了一种在 BCl3 驱动下对炔/烯进行无金属立体选择性分子内氯氨基甲酰化的方法，它为构建双键处具有 (Z) 几何结构的多功能氯化亚甲基内酰胺或四氢异喹啉酮提供了一种通用而实用的方法，其特点是具有立体化学定义的四取代氯乙烯。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

BCl3 catalyzed Z-selective intramolecular chlorocarbamoylation of alkynes/allenes†

查看原文本刊更多论文

BCl3 catalyzed Z-selective intramolecular chlorocarbamoylation of alkynes/allenes†

A metal-free stereoselective intramolecular chlorocarbamoylation of alkynes/allenes driven by BCl₃ was described, which provides a general and practical method for constructing versatile and chlorinated methylene lactams or tetrahydroisoquinolinones with (Z) geometry at the double bond, featuring a stereochemically defined tetrasubstituted chloroethene.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Organic Chemistry Frontiers CHEMISTRY, ORGANIC-

CiteScore

7.90

自引率

11.10%

发文量

686

审稿时长

1 months

期刊介绍： Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.