蜱传病毒:流行病学、发病机制和动物模型

IF 4.1 2区 医学 Q1 INFECTIOUS DISEASES
Kwang-Min Yu , Su-Jin Park
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引用次数: 0

摘要

蜱传病毒可感染动物和人类,其地理分布不断扩大,发病率不断上升,对全球公共卫生构成了重大威胁。本综述探讨了当前人类致病性蜱媒病毒的流行病学,强调了它们的多样性和人类症状表现的范围,从轻微到严重不等。我们强调了病毒爆发的不经常性和不可预测性是如何使精确识别和了解这些病毒在人类感染中的作用变得复杂的。此外,我们还介绍了能准确模拟人类临床症状的动物模型的实用性,这有助于制定有效的控制策略。我们的综合分析提供了对疾病进展的重要见解,并强调了继续研究的迫切需要。这项工作旨在深入了解知识缺口,以减轻蜱媒感染对健康造成的负担,并为进一步研究开辟一条途径,以增进我们对这些新兴传染病的了解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tick-borne viruses: Epidemiology, pathogenesis, and animal models
Tick-borne viruses, capable of infecting animals and humans, are expanding geographically and increasing in prevalence, posing significant global public health threats. This review explores the current epidemiology of human pathogenic tick-borne viruses, emphasizing their diversity and the spectrum of symptomatic manifestations in humans, which range from mild to severe. We highlight how the infrequent and unpredictable nature of viral outbreaks complicates the precise identification and understanding of these viruses in human infections. Furthermore, we describe the utility of animal models that accurately mimic human clinical symptoms, facilitating the development of effective control strategies. Our comprehensive analysis provides crucial insights into disease progression and emphasizes the urgent need for continued research. This work aims to provide insight into knowledge gaps to mitigate the health burden of tick-borne infections and open an avenue for further study to enhance our understanding of these emerging infectious diseases.
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来源期刊
One Health
One Health Medicine-Infectious Diseases
CiteScore
8.10
自引率
4.00%
发文量
95
审稿时长
18 weeks
期刊介绍: One Health - a Gold Open Access journal. The mission of One Health is to provide a platform for rapid communication of high quality scientific knowledge on inter- and intra-species pathogen transmission, bringing together leading experts in virology, bacteriology, parasitology, mycology, vectors and vector-borne diseases, tropical health, veterinary sciences, pathology, immunology, food safety, mathematical modelling, epidemiology, public health research and emergency preparedness. As a Gold Open Access journal, a fee is payable on acceptance of the paper. Please see the Guide for Authors for more information. Submissions to the following categories are welcome: Virology, Bacteriology, Parasitology, Mycology, Vectors and vector-borne diseases, Co-infections and co-morbidities, Disease spatial surveillance, Modelling, Tropical Health, Discovery, Ecosystem Health, Public Health.
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