利用微流体技术进行 DNA 测序的发展历程

IF 39.1 1区生物学 Q1 GENETICS & HEREDITY

Nature Reviews Genetics Pub Date : 2024-09-27 DOI:10.1038/s41576-024-00783-1

Camille L. G. Lambert, Guido van Mierlo, Johannes J. Bues, Orane J. Guillaume-Gentil, Bart Deplancke

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引用次数: 0

摘要

微流控技术的采用是开发具有成本效益的高通量 DNA 测序技术的基础。随着多组学领域的发展，我们思考了微流控技术的关键概念，以及由此产生的微尺度工程技术进步如何推动了基因组测序的发展。微流控技术的采用是开发具有成本效益的高通量 DNA 测序技术的基础。随着多组学领域的发展，Lambert 等人反思了微流控技术的关键概念，以及由此产生的微尺度工程技术进步如何推动了基因组测序的发展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The evolution of DNA sequencing with microfluidics

The adoption of microfluidics was fundamental to the development of cost-effective, high-throughput DNA sequencing. As the field progresses towards multi-omics, we reflect on the key concepts underlying microfluidics and how resulting engineering advances at the microscale drove the evolution of genomic sequencing. The adoption of microfluidics was fundamental to the development of cost-effective, high-throughput DNA sequencing. As the field progresses towards multi-omics, Lambert et al. reflect on the key concepts underlying microfluidics and how resulting engineering advances at the microscale drove the evolution of genomic sequencing.

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来源期刊

Nature Reviews Genetics 生物-遗传学

CiteScore

57.40

自引率

0.50%

发文量

113

审稿时长

6-12 weeks

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