特殊代谢中的β-葡糖苷酶:重新认识植物化学武库的看门人

IF 8.3 2区 生物学 Q1 PLANT SCIENCES
Angeliki Stathaki , Georgia Pantidi , Margarita Thomopoulou , Konstantinos Koudounas
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引用次数: 0

摘要

植物会产生大量特殊的化学物质,以应对充满挑战的环境。尽管特化代谢的结构多种多样,但防御性化合物通常以苷的形式储存在植物体内,而活性苷凝物则由特定的β-葡萄糖苷酶有条件地激活--β-葡萄糖苷酶是一个庞大的酶家族,在植物体内平衡中具有多能性,在植物化学防御中起着关键作用。通常,这些引爆酶具有特殊的底物特异性,在某些情况下,甚至同工酶也表现出不同的分子或生化特征。本文重点介绍了植物β-葡萄糖苷酶引爆防御性化合物的重要内在特征,并着重介绍了对调控机制有新影响的最新研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
β-Glucosidases in specialized metabolism: Towards a new understanding of the gatekeepers of plant chemical arsenal
Plants produce an exceptional multitude of chemicals to compensate with challenging environments. Despite the structural pluralism of specialized metabolism, often defensive compounds are stored in planta as glycosides and reactive aglycones are conditionally activated by specific β-glucosidases—a large family of enzymes with pluripotent contribution in homeostasis and a pivotal role in plant chemical defense. Typically, these detonating enzymes are characterized by exceptional substrate specificity and, in several cases, even isoenzymes exhibit differentiated molecular or biochemical characteristics. This article focuses on important intrinsic characteristics of plant β-glucosidases detonating defensive compounds and highlights recent studies with novel implications in regulatory mechanisms.
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来源期刊
Current opinion in plant biology
Current opinion in plant biology 生物-植物科学
CiteScore
16.30
自引率
3.20%
发文量
131
审稿时长
6-12 weeks
期刊介绍: Current Opinion in Plant Biology builds on Elsevier's reputation for excellence in scientific publishing and long-standing commitment to communicating high quality reproducible research. It is part of the Current Opinion and Research (CO+RE) suite of journals. All CO+RE journals leverage the Current Opinion legacy - of editorial excellence, high-impact, and global reach - to ensure they are a widely read resource that is integral to scientists' workflow.
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