{"title":"特殊代谢中的β-葡糖苷酶:重新认识植物化学武库的看门人","authors":"","doi":"10.1016/j.pbi.2024.102638","DOIUrl":null,"url":null,"abstract":"<div><div>Plants produce an exceptional multitude of chemicals to compensate with challenging environments. Despite the structural pluralism of specialized metabolism, often defensive compounds are stored <em>in planta</em> as glycosides and reactive aglycones are conditionally activated by specific β-glucosidases—a large family of enzymes with pluripotent contribution in homeostasis and a pivotal role in plant chemical defense. Typically, these detonating enzymes are characterized by exceptional substrate specificity and, in several cases, even isoenzymes exhibit differentiated molecular or biochemical characteristics. This article focuses on important intrinsic characteristics of plant β-glucosidases detonating defensive compounds and highlights recent studies with novel implications in regulatory mechanisms.</div></div>","PeriodicalId":11003,"journal":{"name":"Current opinion in plant biology","volume":null,"pages":null},"PeriodicalIF":8.3000,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"β-Glucosidases in specialized metabolism: Towards a new understanding of the gatekeepers of plant chemical arsenal\",\"authors\":\"\",\"doi\":\"10.1016/j.pbi.2024.102638\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Plants produce an exceptional multitude of chemicals to compensate with challenging environments. Despite the structural pluralism of specialized metabolism, often defensive compounds are stored <em>in planta</em> as glycosides and reactive aglycones are conditionally activated by specific β-glucosidases—a large family of enzymes with pluripotent contribution in homeostasis and a pivotal role in plant chemical defense. Typically, these detonating enzymes are characterized by exceptional substrate specificity and, in several cases, even isoenzymes exhibit differentiated molecular or biochemical characteristics. This article focuses on important intrinsic characteristics of plant β-glucosidases detonating defensive compounds and highlights recent studies with novel implications in regulatory mechanisms.</div></div>\",\"PeriodicalId\":11003,\"journal\":{\"name\":\"Current opinion in plant biology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":8.3000,\"publicationDate\":\"2024-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current opinion in plant biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1369526624001298\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PLANT SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current opinion in plant biology","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1369526624001298","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
β-Glucosidases in specialized metabolism: Towards a new understanding of the gatekeepers of plant chemical arsenal
Plants produce an exceptional multitude of chemicals to compensate with challenging environments. Despite the structural pluralism of specialized metabolism, often defensive compounds are stored in planta as glycosides and reactive aglycones are conditionally activated by specific β-glucosidases—a large family of enzymes with pluripotent contribution in homeostasis and a pivotal role in plant chemical defense. Typically, these detonating enzymes are characterized by exceptional substrate specificity and, in several cases, even isoenzymes exhibit differentiated molecular or biochemical characteristics. This article focuses on important intrinsic characteristics of plant β-glucosidases detonating defensive compounds and highlights recent studies with novel implications in regulatory mechanisms.
期刊介绍:
Current Opinion in Plant Biology builds on Elsevier's reputation for excellence in scientific publishing and long-standing commitment to communicating high quality reproducible research. It is part of the Current Opinion and Research (CO+RE) suite of journals. All CO+RE journals leverage the Current Opinion legacy - of editorial excellence, high-impact, and global reach - to ensure they are a widely read resource that is integral to scientists' workflow.