印度 2 型糖尿病患者外周动脉疾病的患病率--系统回顾和荟萃分析

IF 4.3 Q1 ENDOCRINOLOGY & METABOLISM

Diabetes & Metabolic Syndrome-Clinical Research & Reviews Pub Date : 2024-09-01 DOI:10.1016/j.dsx.2024.103124

Esha Arora , Raja Regan , Vyshak Uddur Surendra , Ashokan Arumugam

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引用次数: 0

摘要

背景外周动脉疾病（PAD）是 2 型糖尿病（T2DM）的一种常见并发症。本系统综述的目的是估算印度 T2DM 患者中 PAD 的总体患病率。方法使用特定的检索词检索了从开始到 2023 年 8 月的五个数据库（Cochrane (CENTRAL)、MEDLINE (通过 PubMed)、CINAHL (通过 EBSCO)、PEDro 和 Scopus）。纳入标准包括采用多普勒测试或血压计测量踝肱指数，报告印度成年 T2DM 患者中 PAD 患病率的研究，无论男女。结果有 23 篇文章符合纳入标准，其中包括来自 9 个邦和 1 个中央直辖区的 196,883 名年龄在 30 岁至 70 岁之间的 T2DM 患者。利用随机效应模型进行的荟萃分析表明，印度 T2DM 患者中 PAD 的总体患病率为 18%（95% 置信区间：10%-28%），不同研究之间存在统计学意义上的显著异质性（I2 = 100%，P <0.001）。结论印度 T2DM 患者中 PAD 的总患病率为 18%，这表明印度有相当一部分人受到了影响。利用精确的评估工具进行流行病学研究，可以加强对 T2DM 患者 PAD 的早期发现和预防，并提高研究结果的确定性。

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Prevalence of peripheral arterial disease among individuals with type 2 diabetes mellitus in India - A systematic review and meta-analysis

Background

Peripheral arterial disease (PAD) is a prevalent complication of type 2 diabetes mellitus (T2DM). As India ranks second in the population afflicted by T2DM, and the objective of this systematic review was to estimate the pooled prevalence of PAD in individuals living with T2DM in India.

Methods

Five databases (Cochrane (CENTRAL), MEDLINE (via PubMed), CINAHL (via EBSCO), PEDro, and Scopus) were searched using database-specific search terms from inception to August 2023. Inclusion criteria included studies reporting the prevalence of PAD in Indian adults diagnosed with T2DM of either or both sexes, employing ankle brachial index measurements with a Doppler test or sphygmomanometer. The risk of bias was evaluated using the JBI checklist, and the certainty of evidence was determined via the GRADE approach.

Results

Twenty-three articles met the inclusion criteria which comprised of 196,883 individuals with T2DM aged between 30 and 70 years from nine states and one union territory. Utilizing a random effects model, the meta-analysis revealed that the pooled prevalence of PAD among individuals with T2DM in India was 18 % (95 % confidence interval: 10–28 %), with statistically significant heterogeneity observed between studies (I² = 100 %, P < 0.001). Overall certainty in the evidence was low.

Conclusion

The combined prevalence of PAD among individuals with T2DM in India is 18 %, indicating a significant portion of the Indian population has been affected. Epidemiological studies utilizing precise assessment tools can enhance the early detection and prevention of PAD in T2DM and improve the certainty of findings.

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来源期刊

Diabetes & Metabolic Syndrome-Clinical Research & Reviews ENDOCRINOLOGY & METABOLISM-

CiteScore

22.90

自引率

2.00%

发文量

248

审稿时长

51 days

期刊介绍： Diabetes and Metabolic Syndrome: Clinical Research and Reviews is the official journal of DiabetesIndia. It aims to provide a global platform for healthcare professionals, diabetes educators, and other stakeholders to submit their research on diabetes care. Types of Publications: Diabetes and Metabolic Syndrome: Clinical Research and Reviews publishes peer-reviewed original articles, reviews, short communications, case reports, letters to the Editor, and expert comments. Reviews and mini-reviews are particularly welcomed for areas within endocrinology undergoing rapid changes.