Ziyuan Dai, Qiang Lu, Mingzhong Sun, Hongmei Chen, Rong Zhu, Huiqing Wang
{"title":"在北极狼(Canis lupus arctos)中发现一种新型副病毒。","authors":"Ziyuan Dai, Qiang Lu, Mingzhong Sun, Hongmei Chen, Rong Zhu, Huiqing Wang","doi":"10.33073/pjm-2024-035","DOIUrl":null,"url":null,"abstract":"<p><p>A novel virus, temporarily named \"Arctic wolf parvovirus\" (AWPV), was discovered in a pharyngeal metagenomic library derived from an Arctic wolf (<i>Canis lupus arctos</i>) in China. The genome sequence was assigned GenBase accession number C_AA071902.1. AWPV has a genome comprised of 4,920 base pairs with a nucleotide composition of 36.4% A, 23.4% T, 18.2% G, and 22.0% C, with a GC content of 40.2%. Its structure resembles parvoviruses, containing two open reading frames: the nonstructural (NS) region encoding replication enzymes and the structural (VP) region encoding capsid protein. Pairwise sequence comparison and phylogenetic analysis suggest AWPV may represent a novel species within the genus <i>Protoparvovirus</i>. This discovery enhances our understanding of mammalian virus ecology and potential future infectious diseases.</p>","PeriodicalId":94173,"journal":{"name":"Polish journal of microbiology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11395419/pdf/","citationCount":"0","resultStr":"{\"title\":\"Identification of a Novel Parvovirus in the Arctic Wolf (<i>Canis lupus arctos</i>).\",\"authors\":\"Ziyuan Dai, Qiang Lu, Mingzhong Sun, Hongmei Chen, Rong Zhu, Huiqing Wang\",\"doi\":\"10.33073/pjm-2024-035\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A novel virus, temporarily named \\\"Arctic wolf parvovirus\\\" (AWPV), was discovered in a pharyngeal metagenomic library derived from an Arctic wolf (<i>Canis lupus arctos</i>) in China. The genome sequence was assigned GenBase accession number C_AA071902.1. AWPV has a genome comprised of 4,920 base pairs with a nucleotide composition of 36.4% A, 23.4% T, 18.2% G, and 22.0% C, with a GC content of 40.2%. Its structure resembles parvoviruses, containing two open reading frames: the nonstructural (NS) region encoding replication enzymes and the structural (VP) region encoding capsid protein. Pairwise sequence comparison and phylogenetic analysis suggest AWPV may represent a novel species within the genus <i>Protoparvovirus</i>. This discovery enhances our understanding of mammalian virus ecology and potential future infectious diseases.</p>\",\"PeriodicalId\":94173,\"journal\":{\"name\":\"Polish journal of microbiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11395419/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polish journal of microbiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33073/pjm-2024-035\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/9/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polish journal of microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33073/pjm-2024-035","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Identification of a Novel Parvovirus in the Arctic Wolf (Canis lupus arctos).
A novel virus, temporarily named "Arctic wolf parvovirus" (AWPV), was discovered in a pharyngeal metagenomic library derived from an Arctic wolf (Canis lupus arctos) in China. The genome sequence was assigned GenBase accession number C_AA071902.1. AWPV has a genome comprised of 4,920 base pairs with a nucleotide composition of 36.4% A, 23.4% T, 18.2% G, and 22.0% C, with a GC content of 40.2%. Its structure resembles parvoviruses, containing two open reading frames: the nonstructural (NS) region encoding replication enzymes and the structural (VP) region encoding capsid protein. Pairwise sequence comparison and phylogenetic analysis suggest AWPV may represent a novel species within the genus Protoparvovirus. This discovery enhances our understanding of mammalian virus ecology and potential future infectious diseases.