通过 Ga-68 PSMA PET/CT 成像检测多西他赛诱发的间质性肺炎

IF 0.4 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Indian Journal of Nuclear Medicine Pub Date : 2024-05-01 Epub Date: 2024-08-17 DOI:10.4103/ijnm.ijnm_147_23
Anjali Meena, Bhagwant Rai Mittal, Harmandeep Singh, Girdhar S Bora, Rajender Kumar
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引用次数: 0

摘要

Ga-68标记的前列腺特异性膜抗原(PSMA)正电子发射断层扫描-计算机断层扫描(PET/CT)越来越被认为是疾病分期和检测复发性前列腺癌的最佳成像方式。尽管名为 PSMA,但有报道称 PSMA 在多种非前列腺良性和恶性病变的新血管中均有表达。多西他赛是一种类固醇类抗肿瘤药物,是治疗阉割耐药前列腺癌和高容量激素敏感性前列腺癌的主要药物。虽然与多西他赛相关的间质性肺病很少发生,但如果延误治疗,可能会导致呼吸衰竭。我们报告了一例转移性阉割耐药前列腺癌患者,该患者在接受多西他赛治疗后,在Ga-68 PSMA PET/CT上发现了多西他赛诱发的间质性肺炎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Detection of Docetaxel-induced Interstitial Pneumonitis on Ga-68 PSMA PET/CT Imaging.

Ga-68 labeled prostate-specific membrane antigen (PSMA) positron emission tomography-computed tomography (PET/CT) is increasingly recognized as the best imaging modality for disease staging and detection of recurrent prostate cancer. Despite its name, PSMA expression has been reported in the neovasculature of several nonprostatic benign and malignant pathologies. Docetaxel, a taxane antineoplastic agent, is the mainstay of treatment in castration-resistant prostate cancer and high-volume hormone-sensitive prostate cancer. Although the occurrence of docetaxel-related interstitial lung disease is rare, it may lead to respiratory failure if treatment is delayed. We present a case of metastatic castration-resistant prostate cancer, wherein docetaxel-induced interstitial pneumonitis was detected on Ga-68 PSMA PET/CT after docetaxel administration.

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来源期刊
Indian Journal of Nuclear Medicine
Indian Journal of Nuclear Medicine RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
0.70
自引率
0.00%
发文量
46
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