天然产品作为酪氨酸酶抑制剂。

Q3 Biochemistry, Genetics and Molecular Biology
Enzymes Pub Date : 2024-01-01 Epub Date: 2024-06-25 DOI:10.1016/bs.enz.2024.06.002
Aslınur Doğan, Suleyman Akocak
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引用次数: 0

摘要

酪氨酸酶是一种重要的含铜酶,参与黑色素的生成。黄褐斑、老年斑和雀斑都是黑色素生成过多导致的色素沉着疾病。抑制酪氨酸酶的活性是治疗这些疾病的重要方法,同时还可应用于化妆品、食品技术和医药等多个领域。事实证明,天然产品是酪氨酸酶抑制剂的丰富来源,来自植物、海洋和微生物的多种分子具有潜在的抑制作用。本章全面概述了已发现的酪氨酸酶抑制剂天然化合物,重点介绍了它们的结构、作用模式和应用前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Natural products as tyrosinase inhibitors.

Tyrosinase is a crucial copper-containing enzyme involved in the production of melanin. Melasma, age spots, and freckles are examples of hyperpigmentation diseases caused by excess production of melanin. Inhibiting tyrosinase activity is a crucial method for treating these disorders along with various applications such as cosmetics, food technology, and medicine. Natural products have proven a rich source of tyrosinase inhibitors, with several molecules from plant, marine, and microbial sources showing potential inhibitory action. This chapter provides a complete overview of natural compounds that have been found as tyrosinase inhibitors, with emphasis on their structures, modes of action, and prospective applications.

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来源期刊
Enzymes
Enzymes Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
4.30
自引率
0.00%
发文量
10
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