灾难性抗磷脂综合征:病例报告和文献综述。

IF 1.5 4区 医学 Q3 DERMATOLOGY
Jun Kyoung, Lauren Workman, Taylor Spurgeon-Hess, Kirollos S Tadrousse, Drew Oostra, Richard Simman
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引用次数: 0

摘要

萎缩性抗磷脂综合征(CAPS)是抗磷脂综合征(APS)的一种罕见变体,与快速多器官衰竭有关。APS 与单个中到大型血管闭塞有关,而 CAPS 通常与多个并发的小血管闭塞有关,常见于肾脏、心脏、皮肤和大脑。我们介绍了一例 21 岁的女性患者,她有免疫性血小板减少性紫癜和 APS 病史,最终并发了脑静脉窦血栓、弥漫性肺泡出血、肾血栓性微血管病和前臂坏死性血管炎伤口。尽管她接受了住院治疗,但病情仍不断恶化,最终死于疑似 CAPS。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Catastrophic antiphospholipid syndrome: a case report and literature review.

Catatrophic antiphospholipid syndrome (CAPS), a rare variant of antiphospholipid syndrome (APS), is associated with rapid multiorgan failure. While APS is associated with single medium-to-large blood vessel occlusions, CAPS is most often associated with several, concurrent vascular occlusions of small vessels, commonly of the kidneys, heart, skin and brain. We present a case of a 21-year-old female patient with a history of immune thrombocytopenia purpura and APS, who eventually developed concurrent cerebral venous sinus thrombosis, diffuse alveolar haemorrhage, renal thrombotic microangiopathy, and a necrotic, vasculitic wound on her forearm. Despite hospitalisation and treatment, her condition worsened and the patient eventually died after succumbing to suspected CAPS.

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来源期刊
Journal of wound care
Journal of wound care DERMATOLOGY-
CiteScore
2.90
自引率
10.50%
发文量
215
期刊介绍: Journal of Wound Care (JWC) is the definitive wound-care journal and the leading source of up-to-date research and clinical information on everything related to tissue viability. The journal was first launched in 1992 and aimed at catering to the needs of the multidisciplinary team. Published monthly, the journal’s international audience includes nurses, doctors and researchers specialising in wound management and tissue viability, as well as generalists wishing to enhance their practice. In addition to cutting edge and state-of-the-art research and practice articles, JWC also covers topics related to wound-care management, education and novel therapies, as well as JWC cases supplements, a supplement dedicated solely to case reports and case series in wound care. All articles are rigorously peer-reviewed by a panel of international experts, comprised of clinicians, nurses and researchers. Specifically, JWC publishes: High quality evidence on all aspects of wound care, including leg ulcers, pressure ulcers, the diabetic foot, burns, surgical wounds, wound infection and more The latest developments and innovations in wound care through both preclinical and preliminary clinical trials of potential new treatments worldwide In-depth prospective studies of new treatment applications, as well as high-level research evidence on existing treatments Clinical case studies providing information on how to deal with complex wounds Comprehensive literature reviews on current concepts and practice, including cost-effectiveness Updates on the activities of wound care societies around the world.
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