大量切除标本显示残留基底细胞癌：回顾性病历分析

IF 2.5 3区医学 Q2 DERMATOLOGY

Dermatologic Surgery Pub Date : 2025-02-01 Epub Date: 2024-09-16 DOI:10.1097/DSS.0000000000004399

Ariana J Cecil, Spencer P McClure, Edward W Seger, Nasrin Sultana, Jesalyn A Tate

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引用次数: 0

摘要

背景：建议对基底细胞癌（BCC）进行治疗。然而，患者往往会注意到活检部位似乎已经愈合，并询问是否需要进行额外治疗：本研究旨在确定初次剃须活检后切除标本上残留 BCC 的比率，以帮助决定是否需要进一步治疗：研究人员进行了一项回顾性病历审查，审查了一家医疗机构2012年至2022年间通过活检证实的基底细胞癌切除标本病理报告，以确定是否存在残留肿瘤：符合纳入标准的病例有 217 例。总体而言，39.4%的患者在初次剃须活检后有BCC残留。通过几率比和95%置信区间，发现病变面积较大、活检与切除之间的间隔时间较长以及病变位于高风险身体部位与残留BCC几率增加之间存在显著关系。剃须活检边缘阴性或未指定边缘与残留 BCC 的几率降低之间存在明显关系：结论：研究结果表明，很大一部分患者在初次活检后有残留 BCC。这些结果应纳入医患关于 BCC 治疗方案的讨论中。

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A Large Percentage of Excision Specimens Show Residual Basal Cell Carcinoma: A Retrospective Chart Review.

Background: Treatment of basal cell carcinoma (BCC) is recommended. However, patients often note that the biopsy site appears resolved and inquire about the need for additional treatment.

Objective: This study aims to determine the rate of residual BCC on excision specimens after initial shave biopsy to aid in decision-making on the necessity of further treatment.

Methods and materials: A retrospective chart review was conducted that reviewed excision specimen pathology reports of previously biopsy-proven basal cell carcinomas for the presence of residual tumor between 2012 and 2022 at a single institution.

Results: Two thousand one hundred seventeen cases met inclusion criteria. Overall, 39.4% of patients had residual BCC after an initial shave biopsy. Using an odds ratio and 95% confidence interval, a significant relationship was found between larger lesions, longer time between biopsy and excision, and lesions on high-risk body sites with increased odds of residual BCC. A significant relationship was found between negative or not specified margins on shave biopsy with decreased odds of residual BCC.

Conclusion: The results show that a large percentage of patients have residual BCC following initial biopsies. These results should be included in physician-patient discussions about treatment options for BCC.

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来源期刊

Dermatologic Surgery 医学-皮肤病学

CiteScore

3.10

自引率

16.70%

发文量

547

期刊介绍： Exclusively devoted to dermatologic surgery, the Dermatologic Surgery journal publishes the most clinically comprehensive and up-to-date information in its field. This unique monthly journal provides today’s most expansive and in-depth coverage of cosmetic and reconstructive skin surgery and skin cancer through peer-reviewed original articles, extensive illustrations, case reports, ongoing features, literature reviews and correspondence. The journal provides information on the latest scientific information for all types of dermatologic surgery including: -Ambulatory phlebectomy- Blepharoplasty- Body contouring- Chemical peels- Cryosurgery- Curettage and desiccation- Dermabrasion- Excision and closure- Flap Surgery- Grafting- Hair restoration surgery- Injectable neuromodulators- Laser surgery- Liposuction- Microdermabrasion- Microlipoinjection- Micropigmentation- Mohs micrographic surgery- Nail surgery- Phlebology- Sclerotherapy- Skin cancer surgery- Skin resurfacing- Soft-tissue fillers. Dermatologists, dermatologic surgeons, plastic surgeons, oculoplastic surgeons and facial plastic surgeons consider this a must-read publication for anyone in the field.