男性不育与肥胖

IF 2.6 3区医学 Q3 ENDOCRINOLOGY & METABOLISM

Current Opinion in Endocrinology & Diabetes and Obesity Pub Date : 2024-12-01 Epub Date: 2024-09-09 DOI:10.1097/MED.0000000000000883

Melody A Rasouli, Daniel A Dumesic, Vibha Singhal

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引用次数: 0

摘要

审查目的：最近的发现：活性氧对男性生殖组织的负面影响以及肥胖的发病年龄是男性不育的新研究领域：摘要：这篇综述强调了肥胖如何通过复杂的机制（包括代谢综合征、脂肪毒性、性功能障碍、激素和脂肪因子改变以及表观遗传学变化）损害男性生殖，以及新的管理策略如何改善男性一生的生殖健康。

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Male infertility and obesity.

Purpose of review: The increasing rate of obesity is having an adverse impact on male reproduction.

Recent findings: The negative effect of reactive oxygen species on male reproductive tissues and the age of onset of obesity are new areas of research on male infertility.

Summary: This review highlights how obesity impairs male reproduction through complex mechanisms, including metabolic syndrome, lipotoxicity, sexual dysfunction, hormonal and adipokine alterations as well as epigenetic changes, and how new management strategies may improve the reproductive health of men throughout life.

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来源期刊

Current Opinion in Endocrinology & Diabetes and Obesity ENDOCRINOLOGY & METABOLISM-

CiteScore

5.80

自引率

3.10%

发文量

128

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Endocrinology, Diabetes and Obesity delivers a broad-based perspective on the most recent and exciting developments in the field from across the world. Published bimonthly and featuring twelve key topics – including androgens, gastrointestinal hormones, diabetes and the endocrine pancreas, and neuroendocrinology – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.