青春期后青少年乳头状窦疾病的裂隙提升手术后的长期疗效:来自丹麦前瞻性队列的数据。

IF 2.9 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
J L Ankersen, I K Faurschou, H T Hougaard, D Doll, C Oetzmann von Sochaczewski, M Sørensen, A G Pedersen, S Haas
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引用次数: 0

摘要

目的:蝶窦疾病(PSD)是一种常见病。尽管青春期后青少年患者所占比例相对较大,但目前仅有少量针对这一PSD亚类的研究发表,手术治疗仍具有挑战性:本研究基于兰德斯地区医院2016年建立的前瞻性数据库。从2016年6月到2020年6月,所有接受巴斯康裂隙提升(BCL)手术的患者都被纳入了这项研究,重点是年龄小于18岁的患者,并与成年患者进行比较。BCL手术的适应症为原发性广泛表现、既往选择性手术后疾病未愈合或疾病复发:共有380例PSD患者接受了手术,其中79例为青春期后的青少年,手术时的中位年龄为17.2岁(四分位距为16.3-18.0)。66人(84%)为男孩。27人(34%)有原发性广泛表现,34人(43%)因伤口不愈合而就诊,18人(23%)因复发而就诊。54名患者(69%)的伤口愈合顺利。手术适应症组之间在总体愈合或愈合时间(如果延长)方面没有差异(P = 0.6)。中位随访时间为62个月(四分位数间距为48-73),5年复发率为19%,而成人中的复发率为17%(P = 0.6):我们的研究首次调查了青春期后青少年患者BCL手术治疗PSD的长期临床效果。与成人相比,复发的频率似乎更高。不过,我们的研究表明,青春期后的青少年晚期 PSD 患者可以接受 BCL 手术治疗,且疗效可以接受。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Long-term outcomes after cleft lift surgery for pilonidal sinus disease in post-pubertal adolescents: data from a prospective Danish cohort.

Aim: Pilonidal sinus disease (PSD) is a common condition. Despite a relatively large proportion of patients presenting as post-pubertal adolescents, only small cohorts focusing on this PSD subcategory have been published, and surgical treatment remains challenging.

Method: The study is based on a prospective database established at Randers Regional Hospital in 2016. All patients undergoing Bascom's cleft lift (BCL) surgery from June 2016 until June 2020 were included in this study, focusing on patients ≤18 years of age comparing them to adult patients. Indications for BCL surgery were primary extensive manifestation, non-healing disease after previous elective surgery or disease recurrence.

Results: In total, n = 380 PSD patients were operated, of which n = 79 were post-pubertal adolescents with a median age at time of surgery of 17.2 years (interquartile range 16.3, 18.0). Sixty-six (84%) were boys. Twenty-seven (34%) presented with primary extensive manifestation, 34 (43%) due to non-healing wounds and 18 (23%) due to recurrence. Fifty-four patients (69%) healed uneventfully. There was no difference between the indications of surgery groups in terms of overall healing or time to healing if prolonged (P = 0.6). The median follow-up was 62 months (interquartile range 48, 73), with a 5-year recurrence rate of 19%, compared to 17% (P = 0.6) in the adult population.

Conclusion: Our study is the first to investigate long-term clinical outcomes of BCL surgery for PSD in post-pubertal adolescent patients. Recurrences seem to occur more frequently compared to adults. However, we demonstrate that post-pubertal adolescent patients with advanced PSD can be treated with BCL surgery with acceptable outcomes.

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来源期刊
Colorectal Disease
Colorectal Disease 医学-胃肠肝病学
CiteScore
6.10
自引率
11.80%
发文量
406
审稿时长
1.5 months
期刊介绍: Diseases of the colon and rectum are common and offer a number of exciting challenges. Clinical, diagnostic and basic science research is expanding rapidly. There is increasing demand from purchasers of health care and patients for clinicians to keep abreast of the latest research and developments, and to translate these into routine practice. Technological advances in diagnosis, surgical technique, new pharmaceuticals, molecular genetics and other basic sciences have transformed many aspects of how these diseases are managed. Such progress will accelerate. Colorectal Disease offers a real benefit to subscribers and authors. It is first and foremost a vehicle for publishing original research relating to the demanding, rapidly expanding field of colorectal diseases. Essential for surgeons, pathologists, oncologists, gastroenterologists and health professionals caring for patients with a disease of the lower GI tract, Colorectal Disease furthers education and inter-professional development by including regular review articles and discussions of current controversies. Note that the journal does not usually accept paediatric surgical papers.
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