脱鳞黑色素瘤

IF 2.3 4区医学 Q2 DERMATOLOGY

Clinics in dermatology Pub Date : 2024-09-10 DOI:10.1016/j.clindermatol.2024.09.005

Klaus J Busam

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引用次数: 0

摘要

脱屑性黑色素瘤是黑色素瘤的一种罕见纤维变异型。它通常影响老年患者，但偶尔也会影响年轻人或中年人。去鳞屑黑色素瘤是一种诊断陷阱，因为纯肿瘤变异具有不同的组织病理学和临床特征。后者包括较低的区域淋巴结受累频率以及在厚层黑色素瘤中较好的预后。经典的脱鳞黑色素瘤病例往往具有较高的突变负荷。这些肿瘤转移的患者往往对新型免疫疗法反应良好。

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Desmoplastic melanoma.

Desmoplastic melanoma is a rare fibrosing variant of melanoma. It typically affects elderly patients but can occasionally affect young or middle-aged individuals. Desmoplastic melanoma is relevant as a diagnostic pitfall for pure tumor variants' distinct histopathologic and clinical features. The latter includes a lower regional lymph node involvement frequency and a more favorable prognosis among thick melanomas. Classic cases of desmoplastic melanoma tend to carry a high mutation burden. Patients with metastases from those tumors tend to respond favorably to novel immunotherapies.

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来源期刊

Clinics in dermatology 医学-皮肤病学

CiteScore

4.60

自引率

7.40%

发文量

106

审稿时长

3 days

期刊介绍： Clinics in Dermatology brings you the most practical and comprehensive information on the treatment and care of skin disorders. Each issue features a Guest Editor and is devoted to a single timely topic relating to clinical dermatology. Clinics in Dermatology provides information that is... • Clinically oriented -- from evaluation to treatment, Clinics in Dermatology covers what is most relevant to you in your practice. • Authoritative -- world-renowned experts in the field assure the high-quality and currency of each issue by reporting on their areas of expertise. • Well-illustrated -- each issue is complete with photos, drawings and diagrams to illustrate points and demonstrate techniques.