有非法药物问题的人是否忽视了酒精对健康的长期危害?丹麦吸毒者住院康复中与酒精相关的发病率和死亡率。

IF 2.1 4区 医学 Q3 SUBSTANCE ABUSE
Julie Brummer, Timo Lehmann Kvamme, Birgitte Thylstrup, Morten Hesse
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引用次数: 0

摘要

目的:本研究描述了丹麦接受住院治疗的吸毒者中与酒精相关的发病率和死亡率,并调查了入院治疗时提供的酒精使用自我报告信息是否可用于评估未来与酒精相关的严重危害风险:在基线阶段(2000-2010 年期间开始接受药物使用障碍治疗),患者完成了欧洲改编的成瘾严重程度指数-5。我们利用多个国家登记册对 4981 名患者进行了跟踪调查,直至 2018 年,以确定完全(100%)由酒精导致的医院接触和死亡:结果:可完全归因于酒精的死亡率为每 10 万人年 411 例,平均每人每年可完全归因于酒精的医院接触次数为 0.18 次。在调整后的竞争风险回归模型中,使用成瘾严重程度指数-5酒精综合评分作为预测指标,评分越高,酒精相关死亡风险越高。在调整后的复发性事件模型中,酒精综合评分是与酒精相关的医院接触的重要预测因素:在最初被认定为吸毒障碍的人群中,有相当一部分人存在酒精问题,需要对其进行监测和管理,以防止出现严重的并发症。通过证明自我报告数据的预测能力,我们的研究得出结论:成瘾严重程度指数-5 可用于识别有药物滥用障碍且面临严重长期酒精相关健康后果风险的个体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Are long-term alcohol health harms overlooked in individuals with illicit drug problems? Alcohol-related morbidity and mortality in a Danish cohort of clients in residential rehabilitation for drug use disorders.

Aims: This study described the burden of alcohol-related morbidity and mortality among those who had been enrolled in residential treatment for drug use disorders in Denmark and investigated whether self-reported information on alcohol use provided at treatment admission can be used to assess risk for future serious alcohol-related harms.

Methods: At baseline (entry in drug use disorder treatment during 2000-10), clients completed a European adaptation of the Addiction Severity Index-5. We tracked 4981 clients through 2018 using multiple national registers to identify fully (100%) alcohol-attributable hospital contacts and deaths.

Results: The death rate due to fully alcohol-attributable causes was 411 per 100 000 person-years, with an average of 0.18 fully alcohol-attributable hospital contacts per person-year. Using the Addiction Severity Index-5 alcohol composite score as a predictor in an adjusted competing risks regression model, a higher score was associated with a higher risk of alcohol-related death. The alcohol composite score was a significant predictor of alcohol-related hospital contacts in an adjusted recurrent events model.

Conclusions: A substantial proportion of people originally identified as experiencing drug use disorders have alcohol problems that need to be monitored and managed to prevent serious complications. By demonstrating the predictive power of self-reported data, our study concludes that the Addiction Severity Index-5 can be used to identify individuals with drug use disorders at risk for severe long-term alcohol-related health outcomes.

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来源期刊
Alcohol and alcoholism
Alcohol and alcoholism 医学-药物滥用
CiteScore
4.70
自引率
3.60%
发文量
62
审稿时长
4-8 weeks
期刊介绍: About the Journal Alcohol and Alcoholism publishes papers on the biomedical, psychological, and sociological aspects of alcoholism and alcohol research, provided that they make a new and significant contribution to knowledge in the field. Papers include new results obtained experimentally, descriptions of new experimental (including clinical) methods of importance to the field of alcohol research and treatment, or new interpretations of existing results. Theoretical contributions are considered equally with papers dealing with experimental work provided that such theoretical contributions are not of a largely speculative or philosophical nature.
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