肝移植后Epstein-Barr病毒阴性浆细胞性淋巴瘤

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2024-09-11 eCollection Date: 2024-09-01 DOI:10.14309/crj.0000000000001489

Jonathan K Lin, Lafaine Grant

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引用次数: 0

摘要

浆细胞性淋巴瘤（PBL）属于移植后淋巴组织增生性疾病（PTLD），是一种侵袭性极强的 B 细胞非霍奇金淋巴瘤。自1997年发现以来，肝移植后相关的浆细胞性淋巴瘤病例不到5例。尽管人们对 PTLD 的认识有所提高，影像学技术也有所改进，但 PBL 在确诊时往往表现为播散性疾病。治疗通常包括减少免疫抑制和使用化疗/免疫疗法，但预后仍然很差，中位生存期不到12个月。我们向您介绍一例肝移植后 6 年多发生的 Epstein-Barr 病毒阴性 PBL。

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Epstein-Barr Virus-Negative Plasmablastic Lymphoma Post-liver Transplantation.

Existing on the spectrum of post-transplant lymphoproliferative disorders (PTLD), plasmablastic lymphoma (PBL) is a highly aggressive form of B-cell non-Hodgkin lymphoma. Since its discovery in 1997, fewer than 5 cases of postliver transplantation-associated PBL have been recorded. Despite increased awareness of PTLD and improvement in imaging, PBL often presents with disseminated disease at the time of diagnosis. Treatment usually involves immunosuppression reduction and the use of chemo/immunotherapy, but the prognosis remains poor, with median survival being less than 12 months. We present to you a case of Epstein-Barr virus-negative PBL occurring more than 6 years postliver transplantation.

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.