萎缩性黄斑变性与干细胞疗法：临床回顾。

4区医学 Q2 Biochemistry, Genetics and Molecular Biology

Advances in experimental medicine and biology Pub Date : 2024-09-12 DOI:10.1007/5584_2024_819

Silvia Babighian, Maria Sole Zanella, Irene Gattazzo, Alessandro Galan, Caterina Gagliano, Fabiana D'Esposito, Marco Zeppieri

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引用次数: 0

摘要

老年黄斑变性（AMD）是老年患者视力丧失的主要原因之一。目前还没有治疗这种病症的有效药物，但有研究表明，干细胞疗法可以用视网膜色素上皮（RPE）替代受损的视网膜细胞。本章对干细胞治疗AMD最重要的临床试验和方案进行了临床回顾。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Atrophic Macular Degeneration and Stem Cell Therapy: A Clinical Review.

Age-related macular degeneration (AMD) is one of the leading causes of visual loss in older patients. No effective drug is available for this pathology, but studies about therapy with stem cells replacing the damaged retinal cells with retinal pigment epithelium (RPE) were described. The documentation of AMD progression and the response to stem cell therapy have been performed by optical coherence tomography, microperimetry, and other diagnostic technologies.This chapter reports a clinical review of the most important clinical trials and protocols regarding the use of stem cells in AMD.

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来源期刊

Advances in experimental medicine and biology 医学-医学：研究与实验

CiteScore

5.90

自引率

0.00%

发文量

465

审稿时长

2-4 weeks

期刊介绍： Advances in Experimental Medicine and Biology provides a platform for scientific contributions in the main disciplines of the biomedicine and the life sciences. This series publishes thematic volumes on contemporary research in the areas of microbiology, immunology, neurosciences, biochemistry, biomedical engineering, genetics, physiology, and cancer research. Covering emerging topics and techniques in basic and clinical science, it brings together clinicians and researchers from various fields.